Ovarian Cancer: Is this the Beginning of the End?

August 10, 2019 6:00 pm

By Michael J. Birrer, MD, PhD

There will be 22,530 new cases of ovarian cancer in the United States this year.

Although tumors often present at an advanced stage, it remains one of the most chemosensitive epithelial cancers, with a … Read more

Targeting a Key Protein May Keep Ovarian Cancer Cells from Spreading

July 15, 2019 12:50 pm

By Zachary Sweger

Preventing a protein from doing its job may keep a certain type of ovarian cancer cell from growing and dividing uncontrollably in the lab, according to a new study from Penn State College of Medicine.

In … Read more

Liquid Biopsies Can Point to Best Ovarian Cancer Treatment

May 6, 2019 4:00 pm

DNA shed by tumors into the bloodstream is starting to be used for the early detection of cancer and for monitoring how well treatment is working. Such DNA, which is called circulating tumor DNA (ctDNA), hasn’t been quite as helpful

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Changes in the Metabolism of Normal Cells Promotes the Metastasis of Ovarian Cancer Cells

May 1, 2019 5:00 pm

A systematic examination of the tumor and the tissue surrounding it—particularly normal cells in that tissue, called fibroblasts—has revealed a new treatment target that could potentially prevent the rapid dissemination and poor prognosis associated with high-grade serous carcinoma (HGSC), a … Read more

Crosstalk Between Fallopian Tube, Ovary May Drive the Spread of Ovarian Cancer

October 9, 2018 5:31 pm

New research from the University of Illinois at Chicago shows that cancer cells in the fallopian tube affect normal chemical signaling between reproductive tissues and stimulate the release of norepinephrine, a small molecule hormone, from the ovary.

Reported in ACS Read more

Novel Biomarker Found in Ovarian Cancer Patients Can Predict Response to Therapy

September 27, 2018 6:58 pm

Despite months of aggressive treatment involving surgery and chemotherapy, about 85 percent of women with high-grade wide-spread ovarian cancer will have a recurrence of their disease. This leads to further treatment, but never to a cure. About 15 percent of

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Fallopian Tube Removal May Help Prevent Most Common Ovarian Cancer

December 20, 2017 7:52 pm

A study published in October showed that high-grade serous ovarian carcinomas (HGSOC), which account for about 75 percent of ovarian cancers, originate with abnormal cells in the fallopian tubes an average of seven years before the disease develops. This understanding … Read more