STING Activation Touted as Potential Immunotherapy for Cancer

August 25, 2020 9:00 am

A Scripps Research team reports the discovery of a molecule that can activate a natural immune-boosting protein called STING. The findings mark a key advance in the field of oncology, as the STING protein is known for its strong antitumor … Read more

Ovarian Cancer Metastasis Study Identifies Important Protein with Potential as Diagnostic Tool and Treatment Option

July 16, 2020 3:00 pm

By Clayton Boldt, Ph.D

Advanced ovarian cancer most commonly metastasizes to the omentum, a layer of fatty tissue that wraps around and protects internal organs in the abdomen, but the reasons for this have not been well-understood. In a new … Read more

This MicroRNA Might Help Detect, Treat Ovarian Cancer

June 26, 2020 6:00 pm

In cell and mouse models, miR-181a showed promise as a biomarker for early stage ovarian cancer and may help make immunotherapy treatment more effective.

By Ian Demsky

A microRNA that is normally involved in immune cell differentiation helps to initiate

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New Approach to Stress Out Cancer Cells is Effective in Ovarian Cancer

May 26, 2020 10:00 am

Around 1,500 Australian women will be diagnosed with ovarian cancer this year, and one woman will die every eight hours from this disease.

High-grade serous ovarian cancer (HGSOC) is the most common form of ovarian cancer and accounts for 70%-80% … Read more

New Type of Immunotherapy Hinders the Spread of Ovarian Cancer

March 26, 2020 10:00 am

Malignant ovarian cancer is insidious: Known and feared for vague and uncharacteristic symptoms that often mean the disease is discovered so late that on average only four out of six patients are still alive after five years. Researchers from Aarhus … Read more

Study Shows “Self-eating” Genes may Act as Tumor Suppressors in Ovarian Cancer

February 13, 2020 10:00 am

By Peter Hofland, Ph.D

Scientists at the Medical University of South Carolina (MUSC) and the University of California at San Diego (UCSD) are shedding light on a decades-old controversy, showing that autophagy or “self-eating” genes work against tumors … Read more

Supercharged Cancer Cells Outrun Chemo, Race toward Immunotherapy

February 7, 2020 10:00 am

Cancer cells operate in mutational overdrive, which allows them to blow past chemotherapy and other would-be enforcers of physiological order. Cancer’s speeding, however, may prove to be a vulnerability, say scientists from the Mayo Clinic, the Institute of Cancer Research, … Read more

Researchers find cancer-fighting potential in non-cancer drugs

January 28, 2020 11:00 am

By Julie Steenhuysen

(Reuters Health) – U.S. researchers who tested the cancer-fighting properties of more than 4,500 non-cancer drugs found nearly 50 drugs for other conditions showed at least some cancer-killing ability.

“We found that a surprising number of non-oncology … Read more

Tweaking how CAR-T therapy kills tumors could stop a dangerous side effect, study finds

January 28, 2020 10:00 am

By Sharon Begley

As every trauma surgeon knows, there are messy bullet wounds and there are neat ones, and the former cause incomparably more trouble. If a team of scientists in China is right, the same principle may explain why … Read more

“One-size-fits-all” cancer treatment could be on the horizon after scientists discover new immune cell by accident

January 24, 2020 10:00 am

By Kashmira Gander

Scientists have discovered a new cell in the immune system that can kill many types of cancer, which they hope could one day be used to create a “one size fits all” treatment for the disease.

In … Read more

Small, Thin Metal Mesh Loaded With T Cells Shrinks Tumors in Ovarian Cancer Models

December 9, 2019 6:00 pm

What if a metal that’s already used to repair broken bones, straighten teeth and keep arteries from clogging could also be used to stop your cancer from spreading?

New findings published Dec. 9 in Nature Biomedical Engineering from scientists at … Read more

Researchers Develop Early Detection Test for Ovarian Cancer

August 23, 2019 5:00 pm

Researchers from Queen’s University Belfast have developed a test that may be able to detect ovarian cancer up to two years earlier than current approaches.

The researchers discovered that the presence of four proteins together, known as a biomarker panel, … Read more

Research Shows How Talc Powder May Change Ovarian Cancer Cells

June 18, 2019 6:00 pm

By Sarah Elizabeth Richards

Does talc cause cancer? At least 13,000 people think so, and have filed lawsuits against Johnson & Johnson, the manufacturer of several talcum-based products. Yet so far, juries and scientists have been divided on the … Read more

Novel Treatment Turns Tumors Into ‘Cancer Vaccine Factories’

June 13, 2019 5:00 pm

By Mark L. Fuerst

In-situ vaccine may enhance immunotherapy response in resistant cancers, study shows.

A novel approach to cancer immunotherapy injects immune stimulants directly into a tumor to “teach,” induce the immune system to destroy the cancer and other

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Scientists Uncover Mechanism of Action for Promising Cancer Compound

June 5, 2019 5:00 pm

University of North Carolina Lineberger Comprehensive Cancer Center researchers have uncovered the mechanism that explains how an investigational cancer therapeutic might be working—a finding that they believe could be important for the design of potential new therapies.

In the journal … Read more

Imaging System Helps Surgeons Remove Tiny Ovarian Tumors

April 23, 2019 5:00 pm

By Anne Trafton

More effective surgery could boost survival rates for ovarian cancer.

Ovarian cancer is usually diagnosed only after it has reached an advanced stage, with many tumors spread throughout the abdomen. Most patients undergo surgery to remove as

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Smart Nanoparticles Help Improve Treatment of Peritoneal Tumors

April 22, 2019 5:00 pm

Research carried out at the University of Tartu Faculty of Medicine used nanoparticles for the development of new imaging and treatment methods for peritoneal cancers. Tests showed that precision-guided anticancer nanoparticles have improved efficacy and reduced side effects.

One of … Read more

Targeting Stem-Like Cells Could Prevent Ovarian Cancer Recurrence

March 12, 2019 5:00 pm

Ovarian cancer is not the most common form of cancer, but it’s among the deadliest. That’s because about 70 percent of cases recur. A new study by researchers at the University of Pittsburgh, UPMC Hillman Cancer Center, Magee-Women’s Research Institute … Read more

Cancer Cures and the Importance of Communicating Responsibly

February 6, 2019 3:00 pm

By Carin Canale-Theakston

Xconomy San Diego —  Last week, it was reported by multiple media outlets (see here, and here, and here) that a group of Israeli scientists had found “a cure for all cancer” and that … Read more

Antibody That Targets a Protein on the Surface of Stem Cells Also Targets Same Protein on Cancer Cells

January 17, 2019 5:00 pm
An antibody that targets and is taken up only by certain types of cancer cells has been developed by A*STAR researchers. Combining this antibody with an anticancer drug could lead to a new treatment for some types of breast and… Read more