Targeting a Key Protein May Keep Ovarian Cancer Cells from Spreading

July 15, 2019 12:50 pm

By Zachary Sweger

Preventing a protein from doing its job may keep a certain type of ovarian cancer cell from growing and dividing uncontrollably in the lab, according to a new study from Penn State College of Medicine.

In … Read more

New Program Helps Patients with Advanced Cancer Access Experimental Drugs

July 11, 2019 7:00 pm

By Jack Elliot

In June 2019, the FDA announced a new program called “Project Facilitate” that is designed exclusively for patients with advanced cancer who have exhausted all available treatment options and are unable to participate in clinical trials. Through Read more

The Need for Clinical Trial Navigators

June 20, 2019 5:00 pm

Our Clinical Trial Finder is a personalized and online search tool that will help you to find a clinical trial based on your location or clinical situation (i.e. platinum sensitive or platinum resistant, number of previous treatments). We can also Read more

Novel Treatment Turns Tumors Into ‘Cancer Vaccine Factories’

June 13, 2019 5:00 pm

By Mark L. Fuerst

In-situ vaccine may enhance immunotherapy response in resistant cancers, study shows.

A novel approach to cancer immunotherapy injects immune stimulants directly into a tumor to “teach,” induce the immune system to destroy the cancer and other

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Trial Examines Tolerance of Maintenance Olaparib in Advanced Ovarian Cancer

June 12, 2019 5:00 pm

By Dave Levitan

An analysis of the phase III SOLO1 trial found no new safety signals when the PARP inhibitor olaparib was given as maintenance therapy for women with newly diagnosed advanced ovarian cancer and a BRCA mutation. Nausea, fatigue, … Read more

Does Maintenance Rucaparib Improve Post-Progression Outcomes in Ovarian Cancer?

June 10, 2019 7:00 pm

By Dave Levitan

Maintenance therapy with the PARP inhibitor rucaparib offered improved post-progression outcomes in a phase III trial of patients with recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who were in a complete or partial response to … Read more

SOLO3 Examines Benefit of Olaparib vs Chemo in Platinum-Sensitive Relapsed Ovarian Cancer

June 5, 2019 8:00 pm

By Leah Lawrence

Patients with BRCA-mutated, platinum-sensitive relapsed ovarian cancer derived significant clinical benefit from treatment with olaparib monotherapy compared with treatment of physician’s choice, according to the results of the SOLO3 trial, a US Food and Drug Administration … Read more

Benefit of Single-Agent Carboplatin in Vulnerable, Elderly Patients With Ovarian Cancer

June 5, 2019 7:00 pm

By Leah Lawrence

Single-agent carboplatin conferred significantly worse survival outcomes in vulnerable, elderly patients with stage III/IV epithelial ovarian cancer compared with weekly or every 3 weeks carboplatin/paclitaxel, according to results of the EWOC-1 trial (abstract 5508), which … Read more

Scientists Uncover Mechanism of Action for Promising Cancer Compound

June 5, 2019 5:00 pm

University of North Carolina Lineberger Comprehensive Cancer Center researchers have uncovered the mechanism that explains how an investigational cancer therapeutic might be working—a finding that they believe could be important for the design of potential new therapies.

In the journal … Read more

Chemo-Free Combo Boosts PFS in Recurrent Ovarian Cancer

June 4, 2019 6:00 pm

By Ian Ingram

Benefit seen across all subgroups for patients with platinum-sensitive disease.

Ovarian cancer patients with recurrent, platinum-sensitive disease experienced a longer interval without disease progression when bevacizumab (Avastin) was added to niraparib (Zejula), a phase II study found.… Read more

Medicaid Expansion Narrows Racial Gaps in Access to Timely Ovarian Cancer Care

June 4, 2019 5:00 pm

by Paige Minemyer

Medicaid expansion may have significantly reduced racial disparities in access to earlier ovarian cancer treatment, according to a new study.

The findings, which were presented at the American Society of Clinical Oncology’s annual meeting, show that … Read more

ACA May Impact Ovarian Cancer Outcomes

June 2, 2019 5:00 pm

By John Schieszer

Under the Affordable Care Act (ACA), women with ovarian cancer were more likely to be diagnosed at an early stage and receive treatment within 30 days of diagnosis, according to researchers at Johns Hopkins School of Medicine, … Read more

Choosing Sides: Treatment Decisions for Recurrent Ovarian Cancer Must Consider Side Effects

May 30, 2019 6:00 pm

Patients with ovarian cancer who experience disease recurrences can have potentially helpful options from a large array of drugs, each of which can bring on side effects.

Luckily, doctors have a variety of ways to relieve or prevent these discomforts.

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‘This terrible disease’: Ovarian cancer is deadly, but new tests, treatments start to emerge

May 18, 2019 5:00 pm

By Sarah Elizabeth Richards

Photo: Liz Laats with husband Andy Laats and their three children. She died three years ago of ovarian cancer. The San Diego resident had suffered through 88 rounds of chemotherapy during 10 treatment regimens over six Read more

Study Identifies How Cancer Drug Inhibits DNA Repair in Cancer Cells

May 15, 2019 6:00 pm

According to researchers at Yale Cancer Center, a cancer drug thought to be of limited use possesses a superpower of sorts: It is able to stop certain cancer cells from repairing their DNA in order to survive. The study, published … Read more

Research Could Lead to More Precise Diagnosis and Treatment of Ovarian Cancer

May 8, 2019 5:00 pm

By Michael Brown

Oncologists may soon have an accurate and inexpensive way of differentiating between types of ovarian cancer that will improve how patients are treated, thanks to findings from a national research study co-led out of the University of … Read more

Epithelial Ovarian Cancer: BRCA Mutations, Brain Mets, and Breastfeeding

May 6, 2019 5:00 pm

By Kristin Jenkins

The presence of a BRCA germ line mutation in patients with invasive epithelial ovarian cancer may confer a short-term survival advantage, but is not associated with a reduction in long-term mortality, researchers found.

A follow-up study comparing … Read more

Liquid Biopsies Can Point to Best Ovarian Cancer Treatment

May 6, 2019 4:00 pm

DNA shed by tumors into the bloodstream is starting to be used for the early detection of cancer and for monitoring how well treatment is working. Such DNA, which is called circulating tumor DNA (ctDNA), hasn’t been quite as helpful

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Study Shows Ovarian Cancer Survival Increase

May 3, 2019 5:00 pm

A gynecologic oncologist at the Stephenson Cancer Center at OU Medicine was a national leader of a newly published research study that reveals good news for women with ovarian cancer—longer survival times plus a treatment option that causes fewer difficult … Read more

Managing Chemotherapy Side Effects for Ovarian Cancer

May 1, 2019 5:15 pm

By Dr. Leslie Boyd

Ovarian cancer produces the type of tumor that oncologists like to call “chemo-sensitive”—which is pretty good news for anyone diagnosed. Ovarian cancer cells have been shown to respond well to a combination of chemo drugs, which … Read more