Liquid Biopsies Can Point to Best Ovarian Cancer Treatment

May 6, 2019 4:00 pm

DNA shed by tumors into the bloodstream is starting to be used for the early detection of cancer and for monitoring how well treatment is working. Such DNA, which is called circulating tumor DNA (ctDNA), hasn’t been quite as helpful

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SXSW Panel: ‘Frontiers of Cancer: Racing Toward A Cure’

March 9, 2019 6:00 pm

Clearity’s Executive Director, Hillary Theakston, spoke on a panel of industry leaders at SXSW on ‘Frontiers of Cancer: Racing Toward A Cure’. Hillary, along with fellow panelists Amy Puliafito, Bobbie Rimel, MD, and Karl Handelsman discussed major investments, … Read more

AI Predicts Ovarian Cancer Survival Rates From CT Scans

February 15, 2019 5:00 pm

By Melissa Rohman

AI can predict a woman’s survival rate and response to treatments for ovarian cancer more accurately than current methods, according to research published online Feb. 15 in Nature Communications. 

The machine learning software developed by researchers at … Read more

Many Americans Unaware of Promise of Targeted, ‘Personalized’ Medicine

December 7, 2018 7:00 pm

By Dennis Thompson

Medical science has made tremendous advances in “personalized medicine” — drugs that fight cancer and other diseases by boosting the immune system or targeting specific genetic traits.

Former U.S. President Jimmy Carter benefited from one of these

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Open Source Tool Predicts Chemo Drugs Best Suited for Individual Patients

November 12, 2018 12:09 am

Researchers at Georgia Institute of Technology (Georgia Tech) have developed a new open-source decision support tool designed to help clinicians chose the chemotherapy drug best suited for individual patients.

The open-source support vector machine (SVM)-based algorithm predicted the chemotherapy drug … Read more

Taking A Wider View Of Precision Oncology

August 6, 2018 11:06 pm

Proponents of precision medicine cite the growing numbers of successful precision cancer drugs. The examples of Herceptin (trastuzumab), Gleevec (imatinib mesylate), Xalkori (crizotinib), and Zelboraf (vemurafenib) come to mind. Skeptics, on the other hand, focus on the … Read more

Treating Ovarian Cancers by Targeting Mutations

July 31, 2018 11:22 pm

New research has shown that ovarian cancer patients with a tumor mutation in the BRAF gene respond exceptionally well to treatment with targeted drugs, known as BRAF inhibitors.

BRAF inhibitors block the activity of mutated BRAF gene. They are currently … Read more

Precision Oncology or One Size Fits All?

November 1, 2017 5:42 pm

Platinum/taxane combinations are the most effective regimens for treatment of epithelial ovarian cancer. Response varies between patients, but because the molecular basis for resistance is not defined, patients receive so-called one size fits all therapy. In contrast, elucidation of the … Read more

In Early Study, Rare Tumors Respond To Precision Therapy

October 20, 2017 7:56 pm

By: Bradley J. Fikes

Treatment of rare tumors can be improved with a “precision medicine” approach of matching treatment to the molecular profile of the cancers, according to a preliminary study from UC San Diego researchers.

Tumors stabilized, regressed … Read more

Precision Medicine Rapidly Being Incorporated Into Ovarian Cancer Care

September 22, 2017 7:32 pm

While precision medicine has been a modern go-to approach by physicians in various malignancies, it is demonstrating a particular benefit in ovarian cancer, especially using the method for clinical trial enrollment and in determining whether patients are eligible to receive … Read more

Precision Medicine: A New Era for Ovarian Cancer

September 6, 2017 4:46 pm

By: Laura L. Holman, MD, MS

We’ve come a long way in treating ovarian cancer. This treatment has historically consisted of debulking surgery for nearly every patient, but it is evolving to become more informed and precise. Diagnostic laparoscopy, for … Read more

This Isn’t Your Grandmother’s Ovarian Cancer

June 7, 2017 6:34 pm

By: Hillary Theakston, Executive Director of The Clearity Foundation

In May, for the first time, the U.S. Food and Drug Administration approved a cancer drug for patients whose tumors are defined by a specific genetic feature (biomarker), rather than by … Read more

California Precision Medicine Initiative Unveils $7.2M Funding Opportunity

July 26, 2016 2:40 am

The University of California, San Francisco announced last week that the California Initiative to Advance Precision Medicine (CIAPM) will provide $7.2 million in new funding to support to new precision medicine research projects.

The CIAPM was established in 2015 with … Read more

An Overview of President Obama’s Precision Medicine Initiative

July 14, 2016 6:08 pm

By: Annette McElhiney

Nearly everyone has heard the term Precision Medicine. However most of us have only a shallow understanding of what precision medicine means. To fully understand, go to the government web site and read the President’s initiative in … Read more

Clearity’s Precision Medicine Symposium Demonstrates Sea Change in Personalized Ovarian Cancer Treatment

May 2, 2016 8:38 pm

By: Cory Bentley, PhD

The Society for Gynecological Oncology (SGO) Meeting this March in San Diego brought together physicians and scientists from all over the world to share the latest research, treatments, and thinking in gynecological cancers including ovarian. Clearity … Read more