How Does Ovarian Cancer Form? A New Study Points to MicroRNA

July 30, 2020 4:00 pm

Although ovarian cancer is the fifth-leading cause of death from cancer in women, scientists don’t have a good handle on how it forms. Now a new study suggests that a microRNA—a molecule made by cells to turn genes on … Read more

Universal BRCA Testing Could Prevent Countless Cancer Deaths

July 17, 2020 1:00 pm

By Diana Swift

Population screening found to be cost-effective for higher income countries

Screening entire populations of women for mutations in breast and ovarian cancer susceptibility genes could prevent hundreds of thousands of cases in the U.S., and millions globally, … Read more

A White Paper on the Need for Consistent Terms for Testing in Precision Medicine

July 7, 2020 7:00 am

For years, The Clearity Foundation has emphasized the importance of tumor profiles/blueprints for informing decisions about treatment for ovarian cancer. Yet, genetic and tumor biomarker testing are not universally performed despite evidence that positive results in these tests could suggest … Read more

Convenient Spit Test Helps Women Assess Cancer Risk From The Comfort Of Their Own Homes

June 1, 2020 4:00 pm

By Stand Up To Cancer

Genetic testing for cancer risk can significantly improve the prevention or treatment of hereditary cancers, but studies have shown that people who might have a genetic risk often don’t get tested. A collaborative Stand Up … Read more

Study Findings Support the Use of Video-Assisted Genetic Counseling in Ovarian Cancer

March 31, 2020 10:00 am

By Susan Moench, PhD, PA-C

Results of a randomized clinical trial evaluating video-assisted genetic counseling followed by either formal genetic counseling or direct referral for genetic testing in women with ovarian/fallopian/peritoneal cancer receiving adjuvant therapy showed that a significantly higher … Read more

Pathogenic Variants in RAD51C and RAD51D Linked to Ovarian and Breast-Cancer Risk

March 7, 2020 10:00 am

By Will Boggs MD

NEW YORK (Reuters Health) – Pathogenic variants in RAD51C and RAD51D are associated with an increased risk of ovarian and breast cancer, researchers report.

“RAD51C and RAD51D are included in cancer gene panels that are widely … Read more

ASCO Guideline: Germline Testing Recommended for All Women Diagnosed With Epithelial Ovarian Cancer

February 6, 2020 11:00 am

By Susan Moench, PhD, PA-C

A central tenant of a recently issued American Society of Clinical Oncology (ASCO) guideline is that all women with a diagnosis of epithelial ovarian cancer should be offered testing for specific germline mutations associated with … Read more

PALB2 Linked to Increased Risk for Breast, Ovarian, and Pancreatic Cancer

January 8, 2020 10:00 am

By Christina Bennett, MS

Germline PALB2 pathogenic variants were associated with an increased risk for female breast cancer, male breast cancer, ovarian cancer, and pancreatic cancer, and these risks varied by age, according to data from an international study … Read more

New Name for Breast-Cancer Syndrome Could Help to Save Lives

July 3, 2019 6:00 pm

By Colin C. Pritchard

People of all sexes can have risk genes that are often assumed to affect only women. Renaming the syndrome should aid cancer prevention and treatment, argues Colin C. Pritchard.

I recently had a conversation with my … Read more

CRISPR Reveals New Cancer Drug Targets through ID of Critical Gene Fusion Regions

May 16, 2019 6:00 pm

In what they claim is the first large-scale systematic analysis of thousands of gene fusions in human cancers, scientists have identified a gene fusion that could represent a novel drug target for multiple cancers. Through their studies, the largely U.K.-based … Read more

Scientists Identify Genes Tied to Increased Risk of Ovarian Cancer

May 1, 2019 6:00 pm

A team of researchers at UCLA’s Jonsson Comprehensive Cancer, Cedars-Sinai Cancer and Dana-Farber Cancer Institute have newly identified 34 genes that are associated with an increased risk for developing the earliest stages of ovarian cancer. The findings, published today in … Read more

6 Questions to Ask Your Doctor After an Ovarian Cancer Diagnosis

April 30, 2019 5:00 pm

Two of the key points this article touches on refer to finding a clinical trial and seeking mental health support. At Clearity, we can help! Check out our Clinical Trial Finder, as well as Steps Through OC, a Read more

Ovarian Cancer Patients Undertested for Mutations that Could Guide Clinical Care

April 9, 2019 4:00 pm

By Krista Conger

A large study of women with breast and ovarian cancer has revealed significant gaps between national guidelines for genetic testing and actual testing practices, according to researchers from Stanford and five other institutions.

Fewer than a quarter … Read more

23andMe DTC Breast and Ovarian Cancer Risk Test Misses Almost 90 Percent of BRCA Mutation Carriers

April 5, 2019 5:00 pm

By Julia Karow

A study led by researchers at Invitae has found that 23andMe’s direct-to-consumer BRCA test, which tests for three common variants in the BRCA1 and BRCA2 genes and is authorized by the US Food and Drug Administration, misses … Read more

Only 18% of People With Breast and Ovarian Cancer Genes Knew They Were Carriers, Study Found. How Can We Make DNA Screening Work Better?

February 7, 2019 5:00 pm

By Michael Murray

There are diseases and health conditions that are essentially invisible to us until it is too late.

When those problems are life-threatening, such as cancer, and if there is a period when something could be done, then … Read more

We Asked a Genetic Counselor About 23andMe’s New Cancer Test

January 24, 2019 6:00 pm

By Dan Robitzski

“There’s that element of anxiety and stress and not necessarily having an educational resource to turn to.”

Over The Counter

23andMe is already allowed to screen customers for mutations associated with an increased risk of breast cancer. … Read more

Study Cracks Open the Secrets of the Cancer-Causing BRCA1 Gene

September 12, 2018 12:21 am

By Sharon Begley

Lawsuits didn’t do it, public shaming didn’t do it, patients and doctors banding together to “free the data” couldn’t do it: For 22 years Myriad Genetics, one of the oldest genetic testing companies, has refused to make … Read more

Scientists Identify Mutational Signatures in Ovarian Cancer

August 22, 2018 4:52 pm

Researchers at Cancer Research UK, Imperial College London and the University of Cambridge have identified distinct patterns of genetic mutation among patients with ovarian cancer that could help them understand the disease and personalise treatment … Read more

Study: Cancer-related genetic testing is rare for women on Medicare

August 20, 2018 6:28 pm

By Health Day News

Testing for gene mutations linked to breast and ovarian cancer is rare among some Medicare patients who have the cancers and qualify for such tests, a new study finds.

Researchers analyzed data from 12 southeastern states … Read more

Genetic Screening Can Inform Women of Their Breast and Ovarian Cancer Risks

July 6, 2018 7:21 pm

One of the most unsettling aspects of cancer is the unknown.

There is the unknown of what is in store for you if you receive a diagnosis of cancer. But on a larger scale, we all

Read more