Fertility Concerns a Significant Issue for Gynecologic Cancer Survivors

July 29, 2022 12:59 pm

by Jessica Nye, PhD

A systematic review found that fertility and parenthood were important and affected quality of life for young patients with gynecologic cancers; however, counseling and referral to fertility services is suboptimal. These findings were published in The Read more

Meta-Analysis Examines Link Between Aspirin Use and Ovarian Cancer Risk

July 28, 2022 10:32 am

by The ASCO Post Staff

Frequent aspirin use may be linked with lower ovarian cancer risk in individuals with multiple risk factors, according to a new study published by Hurwitz et al in the Journal of Clinical Oncology.

“Ovarian … Read more

Effects of Food Insecurity Interventions on Cancer Treatment Adherence, Completion

July 13, 2022 11:22 am

by Vicki Moore, PhD

A recent study evaluated the effects programs aimed at addressing food insecurity have on treatment outcomes for patients with cancer. Each intervention seemed beneficial, with a voucher-plus-pantry program appearing to be the most effective. The study’s … Read more

Examining factors that may impact ovarian cancer survival disparities

June 20, 2022 10:33 am

by Coco Davis/ Fred Hutchinson Cancer Research Center

Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy among women in the United States (US). Although the incidence rate is higher among White women, Black women have the lower survival … Read more

Tool improves women’s ‘sense of control’ over ovarian cancer symptoms

June 18, 2022 12:08 pm

by Jennifer Byrne

Women with recurrent ovarian cancer experience an average of 14 disease or treatment-related symptoms at any given time over the course of their disease.

“It’s a huge symptom burden,” Heidi Donovan, PhD, RN, professor of health and … Read more

Ovarian cancer survivors have shown resilience in the face of the pandemic, but are still at risk for mental health challenges

June 8, 2022 5:08 pm

by University of Chicago Medical Center

Clearity offers psychosocial support through our Steps Through OC program for patients, survivors and caregivers. If you would like personal one-to-one assistance with the stress and challenges associated with an ovarian cancer diagnosis, our

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Break Through Cancer Announces $50 Million in Grants to Researchers From Five Top Cancer Research Centers

April 19, 2022 9:13 am

by the ASCO Post Staff

Today, 1 year after its founding, Break Through Cancer announced $50 million in grants to support several cutting-edge research projects using a novel “TeamLab” structure—designed to maximize interdisciplinary collaboration among researchers at Dana-Farber Cancer Institute, … Read more

Multifactorial Strategy Shows Promise For Lethal Ovarian Cancer

April 12, 2022 2:28 pm

Scientists from the University of California (UC), San Diego, and their collaborators have demonstrated how key proteins act together to suppress antitumor activity in high-grade serous ovarian carcinoma (HGSOC) in a mouse model, revealing a new combinatorial strategy to treat Read more

New Clue to Risk of Peritoneal Cancer After Prophylactic Salpingo-Oophorectomy

April 5, 2022 3:27 pm

by Charles Bankhead

— Women with BRCA variant and serous tubal intraepithelial carcinoma had a 34-fold greater risk

The presence of serous tubal intraepithelial carcinoma (STIC) at the time of risk-reducing salpingo-oophorectomy (RRSO) significantly increased the risk of peritoneal carcinomatosis … Read more

Researchers Use US to Predict Ovarian Cancer

March 22, 2022 11:13 am

Approach can help radiologists in a busy clinical practice assess lesions more quickly

The appearance of ovarian lesions on ultrasound is an effective predictor of cancer risk that can help women avoid unnecessary surgery, according to a new study published … Read more

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

March 16, 2022 9:43 am

by Emily Henderson, B.Sc.

High-grade serous carcinoma is the most aggressive form of ovarian cancer and accounts for the majority of advanced-stage cases. The poor outcomes associated with the disease underscore the need for more effective treatments. A research team … Read more

‘Drug factory’ implants eliminate ovarian, colorectal cancer in mice

March 2, 2022 11:45 am

by Jade Boyd

Rice immunotherapy treatment could begin human clinical trials this year

HOUSTON – (March 2, 2022) – Rice University bioengineers have shown they can eradicate advanced-stage ovarian and colorectal cancer in mice in as little as six days

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Ovarian Cancer Chemotherapy Resistance Linked to Stress-Associated Gene Expression Features

February 23, 2022 9:24 am

NEW YORK – A team led by researchers at the University of Helsinki has uncovered stress-related tumor and microenvironment gene expression features that appear to coincide with chemotherapy resistance and shorter progression-free survival in individuals with high-grade serous ovarian cancer.… Read more

The secret hideouts of ovarian cancer revealed

February 11, 2022 9:53 am

Every year, roughly 550 women develop ovarian cancer in Finland. Ovarian cancer is difficult to treat and it is commonly fatal, with 320 women dying of ovarian cancer annually in Finland.

Cancer can only develop and progress when the tumour … Read more

Online tool helps ovarian cancer patients feel more in control of symptoms

February 8, 2022 9:38 am

PITTSBURGH – An online symptom management tool that harnesses the problem-solving benefits of expressive writing could help women with ovarian cancer better manage complex symptoms, according to a new study led by a University of Pittsburgh and UPMC nurse-scientist.

Published … Read more

Small device for earlier ovarian cancer detection

January 19, 2022 8:40 am

by Emily Dieckman

Jennifer Barton, director of the University of Arizona BIO5 Institute and Thomas R. Brown Distinguished Chair in Biomedical Engineering, has spent years developing a device small enough to image the fallopian tubes. Credit: Chris Richards/University of ArizonaRead more

Study Shows How Ovarian Cancer Starts in High-Risk Women

December 28, 2021 10:47 am

by Cedars-Sinai

Findings Hold Potential for Predicting Many Years in Advance Which Women With the BRCA-1 Mutation Will Develop Disease

Newswise — Los Angeles (December 28, 2021). –Ovarian cancer is the leading cause of gynecologic cancer deaths in the U.S., … Read more

Biomarkers Found for Platinum Resistance in Gynecologic Cancer

November 19, 2021 11:56 am

Blood-based metabolic signatures may predict whether women with ovarian or uterine cancer will respond well to platinum-based chemotherapy, according to a study by researchers in the Department of Gynecology at the Federal University of São Paulo’s Medical School (EPM-UNIFESP) in … Read more

MCW scientists uncover potential therapeutic target and biomarker for ovarian cancerPortfolio Inspiration

November 17, 2021 11:28 am

MEDICAL COLLEGE OF WISCONSIN

The study’s findings suggest targeting protein FXR1 to inhibit the progression of the cMYC oncogene, a gene mutation often over-expressed in patients with ovarian cancer

Scientists at the Medical College of Wisconsin (MCW) Cancer Center and … Read more

Addition of Bevacizumab to Pembrolizumab Improves Responses in Epithelial Ovarian Cancer

November 17, 2021 10:25 am

By Courtney Marabella

The addition of a short-term, flat dose of bevacizumab to pembrolizumab was found to enhance the response to anti–PD-1 therapy in the absence of chemotherapy for patients with platinum-resistant epithelial ovarian cancer.

The addition of a short-term,

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