Patients With Cancer Deserve Respect, Civility and a Voice in Their Treatment

October 6, 2021 12:00 am

By Kelly Irvin

Health care isn’t something that is done to you. You participate in it. You’re part of the team. If your team is letting you down, say so. If they don’t do better, consider seeking health care providers Read more

How ovarian cancers evade the immune system

October 6, 2021 12:00 am

By Krista Conger

It’s diabolical, and so clever. Recent research by cancer biologist Wendy Fantl, PhD, and immunologist and cancer biologist Veronica Gonzalez, PhD, shows that ovarian tumors thrive by convincing nearby immune cells that the cancer cells are those … Read more

Women with genetic mutations fare no worse with breast or ovarian cancer, study finds

October 1, 2021 12:00 am

By Krista Conger

Newly diagnosed breast or ovarian cancer patients who carry common cancer-associated mutations have similar or better short-term survival rates than those with no mutations, researchers report.

Women newly diagnosed with breast or ovarian cancer who are also … Read more

Third COVID Vaccine Dose Boosts Protection in Solid Tumor Patients

October 1, 2021 12:00 am

By Mike Bassett

— For those on active therapy, 80% had increased antibody levels, study showed

A third dose of Pfizer’s COVID-19 vaccine (BNT162b2; Comirnaty) could offer increased protection for cancer patients on active treatment, a new study suggested, as … Read more

Biomarker May Help to Predict Response to Gemcitabine for Patients With High-Grade Serous Ovarian Cancer

September 30, 2021 2:05 am

By The ASCO Post Staff

For more than 2 decades, the chemotherapy agent gemcitabine has been a mainstay treatment for several types of cancer. Now, scientists have uncovered genetic evidence of which patients with high-grade serous ovarian cancer are likely … Read more

Neoadjuvant Chemo for Advanced Ovarian Cancer Reduced Short-Term Mortality

September 30, 2021 12:00 am

By Mike Bassett

— Programs frequently using this treatment achieved these declines without compromising OS

Cancer programs that were more likely to use neoadjuvant chemotherapy to treat advanced ovarian cancer saw larger declines in short-term mortality versus programs with less … Read more

What Patients With Ovarian Cancer Should Know About Maintenance Therapy

September 29, 2021 10:05 am

By Jamie Cesanek

Maintenance therapy is meant to prevent relapse after a patient with ovarian cancer received their main treatment. Here’s an overview of what patients should know.

When a patient is diagnosed with ovarian cancer, their initial treatment typically

Read more

Symptoms of Ovarian Cancer Explained as Woman Diagnosed Thanks to Small Navel Growth

September 28, 2021 12:00 am

By Aatif Sulleyman

A woman is raising awareness of ovarian cancer and how difficult it can be to detect, having been diagnosed with the illness by a dermatologist who removed a small growth from her navel.

Despite being aware of … Read more

Attachment Insecurity and Depression, Anxiety in Ovarian Cancer Patient Partner-Caregivers

September 24, 2021 12:00 am

By Jessica Nye, PhD

A cross-sectional study found that caregivers of patients with ovarian cancer were experiencing symptoms of depression and anxiety which were affected by attachment avoidance. These findings were published in Current Oncology.

Caregivers are an important … Read more

Ovarian Cancerx: New Innovative Clinical Research Effort Seeks to Accelerate the Development of New Treatments for Deadliest Gynecological Cancer

September 23, 2021 9:19 am

LOS ANGELES – (BUSINESS WIRE)–Global Coalition for Adaptive Research (GCAR) announces a new clinical trial initiative, Ovarian CanceRxTM. This innovative trial, referred to as an adaptive platform trial, is designed to test multiple drugs simultaneously against the … Read more

Wistar Scientists Identify New Therapeutic Target in Ovarian Cancer Subtype With Poor Prognosis. Ovarian clear cell carcinomas with ARID1A mutations are sensitive to inhibition of the IRE1a-XBP1 stress response pathway in preclinical models.

September 21, 2021 5:12 pm

By Wistar Institute

Newswise — PHILADELPHIA — (Sept. 21, 2021) — Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists at The Wistar Institute discovered … Read more

Drug combination shows promise in treatment-resistant advanced ovarian cancer

September 19, 2021 3:59 pm

A new combination of targeted drugs for a type of ovarian cancer has shown promising results in an early clinical trial – shrinking tumours in half of patients.

The combination of drugs – which both work by blocking signals cancer … Read more

Intermittent Relacorilant Combined with Nab-paclitaxel Improves PFS in Recurrent Platinum-Resistant Ovarian Cancer

September 17, 2021 4:47 pm

In the first randomised, controlled study to explore the efficacy and safety of relacorilant, a selective glucocorticoid receptor modulator, in combination with nab-paclitaxel compared to nab-paclitaxel alone, combined treatment improved progression-free survival (PFS) and showed a favourable safety profile among … Read more

Rechallenge With PARP Inhibitor Slows Relapsed Ovarian Cancer

September 17, 2021 4:10 pm

— Benefits platinum-sensitive disease irrespective of BRCA, homologous repair status, study showed

Patients with relapsed platinum-sensitive ovarian cancer had significant improvement in progression-free survival (PFS) when retreated with the PARP inhibitor olaparib … Read more

Nivolumab vs Gemcitabine or Pegylated Liposomal Doxorubicin: What Regimen Improves Survival in Platinum-Resistant Ovarian Cancer?

September 15, 2021 10:44 am

By Matthew Stenger

In a Japanese phase III trial (NINJA) reported in the Journal of Clinical Oncology, Hamanishi et al found that nivolumab did not improve overall survival vs chemotherapy with either gemcitabine or pegylated liposomal doxorubicin in platinum-resistant epithelial … Read more

NCCN Issues Updated Guidelines Regarding Third COVID-19 Vaccine Booster for Those With Cancer

August 30, 2021 5:18 pm

By Hayley Virgil

Updates to the National Comprehensive Cancer Network guidelines on the COVID-19 vaccine for patients with cancer indicate that this group should be prioritized for a third dose.

The National Comprehensive Cancer Network (NCCN) has announced a significant … Read more

Finding cancer earlier: New tests show promise with broader screening available

August 19, 2021 9:33 pm

By Meg Tully

Rosemary Jemo volunteered for a blood test trial based on pioneering research from Johns Hopkins University because she thought it would be great if it could save lives.

The 71-year-old Pennsylvania hairdresser now believes that decision saved … Read more

Researchers pinpoint how PARP inhibitors combat BRCA1 and BRCA2 tumor cells

August 13, 2021 9:27 pm

A team of Massachusetts General Hospital (MGH) researchers has discovered how an important class of anti-cancer drugs called PARP inhibitors works, a finding that could help improve treatment and prolong survival for patients with breast cancer and other malignancies.… Read more

Changes in Clinical Trial Conduct Prompted by the COVID-19 Pandemic Should Persist

August 5, 2021 3:51 pm

By Alan P. Lyss, MD

The COVID-19 pandemic prompted changes to standard practices for cancer clinical trials, and thought leaders have recommended continuing — and improving upon — those new practices.

These recommendations, from members of the American Association for … Read more