Women with genetic mutations fare no worse with breast or ovarian cancer, study finds

October 1, 2021 12:00 am

By Krista Conger

Newly diagnosed breast or ovarian cancer patients who carry common cancer-associated mutations have similar or better short-term survival rates than those with no mutations, researchers report.

Women newly diagnosed with breast or ovarian cancer who are also … Read more

Biomarker May Help to Predict Response to Gemcitabine for Patients With High-Grade Serous Ovarian Cancer

September 30, 2021 2:05 am

By The ASCO Post Staff

For more than 2 decades, the chemotherapy agent gemcitabine has been a mainstay treatment for several types of cancer. Now, scientists have uncovered genetic evidence of which patients with high-grade serous ovarian cancer are likely … Read more

Improving Social Needs For Women With Gynecological Cancer Could Improve Outcomes and Lessen Healthcare Disparities

August 4, 2021 4:04 pm

By Ariana Pelosci

Women with gynecologic cancer who experience an improvement of social needs such as companionship and food insecurity could experience improved outcomes.

The identification of social needs and accompanying solutions could result in more actionable health care disparities … Read more

Virtual biopsies may give more accurate results than traditional method thanks to revolutionary technique

July 11, 2021 3:17 pm

CAMBRIDGE, England — Virtual biopsies could replace invasive tissue procedures and give more accurate results thanks to a revolutionary new method developed using computer scans. The new advanced computing technique uses routine medical scans to enable doctors to take fewer, … Read more

‘Devastated and Sad’ After 36 Years of Research — Early Detection of Ovarian Cancer Doesn’t Save Lives

May 19, 2021 1:00 pm

By Professor Ian Jacobs

I was motivated to improve the outcome for women with ovarian cancer by my experience as a junior doctor in London in 1985. But 36 years on, the results aren’t what we’d hoped.

My colleages’ and

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Disappointment: Screening for Ovarian Cancer Does Not Cut Deaths

May 13, 2021 12:00 pm

By Pam Harrison

Results from a huge British trial that involved more than 200,000 women who were followed for a median of 16 years have turned out negative. Investigators found that annual screening for ovarian cancer with either multimodal screening … Read more

Smart Cell Therapies for Solid Cancers Ready to Move Toward Clinical Trials

April 28, 2021 7:00 pm

By Lindzi Wessel

Immunotherapies that fight cancer have been a life-saving advancement for many patients, but the approach only works on a few types of malignancies, leaving few treatment options for most cancer patients with solid tumors. Now, in two Read more

HIPEC Combo Doubles PFS in Advanced Ovarian Cancer

March 26, 2021 12:00 pm

Cisplatin/paclitaxel boosts outcomes without increasing complications in registry study.

By Charles Bankhead

Two drugs outperformed one for hyperthermic intraperitoneal chemotherapy (HIPEC) after interval surgical debulking of advanced ovarian cancer, data from a prospective registry showed.

Median progression-free survival (PFS) doubled … Read more

Moffitt Researchers Discover Mechanism that Regulates Anti-Tumor Activity of Immune Cells

February 3, 2021 3:00 am

The study finally paves the way for the use of antibodies different from IgG as immunotherapeutic agents for at least tumors currently resistant to conventional immune checkpoint blockade.

The prognosis of ovarian cancer is poor, with an estimated five-year survival … Read more

‘Virtual Biopsies’ Could Replace Tissue Biopsies in Future Thanks to Technique Developed by Cambridge Scientists

January 6, 2021 5:00 am

A new advanced computing technique using routine medical scans to enable doctors to take fewer, more accurate tumour biopsies, has been developed by cancer researchers at the University of Cambridge. This is an important step towards precision tissue sampling for

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In Vitro Fertilization Does Not Increase the Risk of Ovarian Cancer

November 20, 2020 7:00 pm

A new paper published in JNCI: Journal of the National Cancer Institute indicates that receiving assisted reproductive technology does not increase the risk women have for developing ovarian cancer.

Previous research indicated that women who use assisted reproductive technology in Read more

‘Next-Gen’ Immunotherapy Active in Advanced Cancers

November 16, 2020 5:00 pm

Disease control in two-thirds of patients treated with bispecific antibody.

By Charles Bankhead

An investigational drug that combines PD-1/L1 inhibition and T-cell stimulation led to disease control in two-thirds of patients with unresectable advanced solid malignancies, a preliminary clinical study … Read more

SRS Instead of WBRT for Patients With Multiple Brain Metastases

October 29, 2020 3:00 pm

 Roxanne Nelson, RN, BSN

Stereotactic radiosurgery (SRS) should replace whole-brain radiotherapy (WBRT) as the new standard of care for patients with four or more brain metastases, say researchers who report results from a randomized trial conducted in patients with … Read more

Adagrasib a Promising New Treatment for Lung, Pancreatic, Endometrial, Ovarian and Colon Cancers

October 27, 2020 6:00 pm

By Mary Moore

A new drug that inhibits a cancer mutation in the KRAS gene has shown encouraging results in patients with lung cancer, colon cancer, and other solid tumors.

For decades, scientists have been trying to develop new … Read more

Research Discovery May Offer New Treatment Options for People Diagnosed With Rare Form of Ovarian Cancer

August 26, 2020 8:00 am

A recent finding by researchers at UBC’s faculty of medicine and the BC Cancer Research Institute (BCCRI) may offer a new treatment possibility for people diagnosed with a rare and aggressive form of ovarian cancer.

Small cell carcinoma of the … Read more

HIPEC With Cytoreductive Surgery Effective in Ovarian Cancer

August 25, 2020 5:00 pm

By Sarah Williams

For patients with stage III epithelial ovarian cancer, adding hyperthermic intraperitoneal chemotherapy (HIPEC) to primary cytoreductive surgery (PCS) increases survival compared with PCS alone, according to results of a retrospective study now published in JAMA Network OpenRead more

Tumor Gene Test Could Help to Predict Ovarian Cancer Prognosis

August 17, 2020 6:00 pm

A global team of medical researchers led by UNSW have developed a test that could help to predict survival for women diagnosed with ovarian cancer, and pave the way towards personalised treatment.

A tumour test could help to identify ovarian … Read more

Local Resident Oversees Potential COVID-19 Pneumonia Treatment

August 10, 2020 1:00 pm

By Luke Harold

As chairman and CEO of CalciMedica, Rachel Leheny is overseeing the development of a potential treatment for organ damage caused by COVID-19 pneumonia.

“Our lead compound Auxora is in clinical development in COVID-19 pneumonia,” said Leheny, who … Read more

Study Finds Patients With Rare Ovarian Cancer Develop Chemoresistance

August 7, 2020 5:00 pm

By Christina Bennett, MS

Patients with LGSC also had a significantly lower partial response rate with neoadjuvant therapy compared with patients with HGSC.

Patients with low-grade serous carcinoma of the ovary or peritoneum (LGSC) developed chemoresistance to neoadjuvant platinum-based therapy,

Read more

How Does Ovarian Cancer Form? A New Study Points to MicroRNA

July 30, 2020 4:00 pm

Although ovarian cancer is the fifth-leading cause of death from cancer in women, scientists don’t have a good handle on how it forms. Now a new study suggests that a microRNA—a molecule made by cells to turn genes on … Read more