Tag: Clinical Research
Ovarian Cysts Should Be ‘Watched’ Rather Than Removed
February 5, 2019 5:00 pmWomen may not need to undergo surgery for non-cancerous ovarian cysts, avoiding potential surgical complications.
This is the finding of new research, by a team of international scientists from institutions including Imperial College London and KU Leuven, published in The … Read more
Drug Treating Breast Cancer May Be Effective in Treating Lung and Ovarian Cancer
February 5, 2019 4:00 pmTwo new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two different types of cancer, one rare … Read more
Drug Target Identified for Chemotherapy-Resistant Ovarian, Breast Cancer
February 4, 2019 5:00 pmBy Tamara Bhandari
Study finds mimic for BRCA genes that could be targeted to improve treatment
People who inherit a faulty copy of the so-called “breast cancer genes” BRCA1 and BRCA2 are at high risk of cancer. About 10 percent … Read more
Energizing the Immune System to Eat Cancer
January 21, 2019 3:00 pmImmune cells called macrophages are supposed to serve and protect, but cancer has found ways to put them to sleep. Now researchers at the Abramson Cancer Center of the University of Pennsylvania say they’ve identified how to fuel macrophages with … Read more
AI Tool Scans Tumour Shape to Detect Aggressive Ovarian Cancer
January 15, 2019 12:30 amResearchers at The Institute of Cancer Research, London (ICR) have developed an artificial intelligence (AI) test that analyses the shape of tumour cells to identify patients with aggressive ovarian cancer.
The test is intended to enable tailored treatment based on … Read more
Palliative Care May Improve Survival, Quality of Life in Advanced Cancer
January 14, 2019 5:30 pmBy Brielle Benyon
Recent research found that outpatient palliative care improved survival and quality of life in patients with advanced cancer.
Palliative care may boost survival in patients with advanced cancer, according to recent research conducted at Tulane University.
“If … Read more
PCOS May Increase Overall Cancer Risk
December 13, 2018 5:00 pmBy Regina Schaffer
Swedish women with polycystic ovary syndrome are 15% more likely to develop any cancer vs. women without the condition, with risk further elevated for cancers of the endometrium, ovary, pancreas and kidney, according to a research letter … Read more
Cancer DNA Binds to Gold. That Could Lead to New Cancer Blood Test.
December 5, 2018 7:30 pmBy
Researchers have discovered a curious difference between the DNA from cancer cells and that from healthy cells, and this finding could lead to a new blood test for cancer.
The difference? Cancer DNA has a … Read more
Sound and Light Could Detect Ovarian Cancer Earlier
November 23, 2018 11:32 pmBy Beth Miller
Researchers have found an innovative way to use sound and light, or photoacoustic, imaging to diagnose ovarian tumors. The method may lead to a promising new diagnostic imaging technique to improve current standard of care for patients … Read more
Ultrasonography Useful for Predicting Ovarian Cancer Risk
November 21, 2018 9:55 pmBy Will Boggs MD
The ultrasonographic appearance of ovarian masses is strongly associated with a woman’s risk of ovarian cancer, researchers report.
“Ovarian cancer is a frightening and devastating disease, and we want to be able to find ovarian cancer … Read more
New Dual-Action Cancer-Killing Virus
November 18, 2018 8:00 pmScientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system.
It is the first time that cancer-associated fibroblasts … Read more
Ultrasound Finds Simple Cysts Not Associated With Ovarian Cancer Risk
November 13, 2018 3:00 pmUsing ultrasound technology, researchers found simple ovarian cysts—commonly found amongst premenopausal and postmenopausal women—are not associated with an increased risk of ovarian cancer and do not require additional surveillance or surgical intervention, according to research published online
Open Source Tool Predicts Chemo Drugs Best Suited for Individual Patients
November 12, 2018 12:09 amResearchers at Georgia Institute of Technology (Georgia Tech) have developed a new open-source decision support tool designed to help clinicians chose the chemotherapy drug best suited for individual patients.
The open-source support vector machine (SVM)-based algorithm predicted the chemotherapy drug … Read more
Ovarian Cancer Risk Reduced with Postmenopausal Statins
November 7, 2018 5:00 pmBy Pam Harrison
All histologic types of ovarian cancer risk lowered in statin versus non-statin users.
Women who started taking a statin at the age of 50 or older had a significantly lower risk of developing any histologic type of … Read more
Real-World Experience Differs from Trial Results for Niraparib in Recurrent Ovarian Cancer
October 25, 2018 1:11 amReal-world experience of adverse events with the oral PARP inhibitor niraparib in patients with platinum-sensitive recurrent ovarian cancer at a 200 mg daily dose differed from those most commonly seen in the phase 3 clinical trial at … Read more
Ovarian Cancer Thwarts Immune Cells by Revving up Stress
October 12, 2018 11:30 pmOvarian tumors disable the immune system’s killer T cells—which protect the body by destroying infected or malignant cells—enabling the disease to flourish unchecked, according to a new study by Weill Cornell Medicine scientists. The findings show that adverse conditions within … Read more
Low-Dose Aspirin May Lower Ovarian Cancer Risk
October 4, 2018 1:15 am
BRCA1 Methylation Level May Predict Which Ovarian Cancer Patients Respond to PARP Inhibitors
September 28, 2018 8:37 pmThe extent to which the BRCA1 promoter is methylated could signal an ovarian tumor’s susceptibility to PARP inhibitor treatment, a new study has found.
PARP inhibitor treatment has been effective in treating some patients with high-grade serous ovarian carcinoma with … Read more
Novel Biomarker Found in Ovarian Cancer Patients Can Predict Response to Therapy
September 27, 2018 6:58 pmDespite months of aggressive treatment involving surgery and chemotherapy, about 85 percent of women with high-grade wide-spread ovarian cancer will have a recurrence of their disease. This leads to further treatment, but never to a cure. About 15 percent of
… Read more