Treatment with Lipophilic Statins Shows Lower Mortality Rate for Patients with Epithelial Ovarian Cancer

June 22, 2020 6:00 pm

A study presented at the AACR Virtual Annual Meeting II showed a significant decrease in mortality rate for patients with epithelial ovarian cancer when treated with lipophilic statins, supporting the further evaluation of statins to treat ovarian cancer in randomized Read more

Single-Cell Analysis of Ovarian Cancer Points to Potential Treatment Avenue

June 22, 2020 10:00 am

Inhibiting the JAK/STAT pathway could represent a potential treatment for high-grade serous ovarian cancer, according to a single-cell analysis.

Researchers led by the Broad Institute’s Aviv Regev used single-cell RNA sequencing (scRNA-seq) to analyze about 11,000 cells from ascites from … Read more

New Test Paves the Way for Tailored Treatment of Deadliest Form of Ovarian Cancer

June 18, 2020 4:00 pm

University of British Columbia (UBC) researchers have led an international team in developing a new test to better diagnose different types of ovarian cancer, a tool that could one day guide and improve treatment options for women diagnosed with the … Read more

Water-Only Fasting May Reduce Chemo Modifications, Hospital Admissions

April 3, 2020 10:00 am

By Neil Osterweil

FROM SGO 2020

Patients with gynecologic malignancies who consumed only water for 24 hours before and 24 hours after each chemotherapy cycle had fewer dose delays and reductions compared with patients who didn’t fast, results of a

Read more

Barriers to Clinical Trial Participation Revealed By Gynecologic Cancer Patients

March 31, 2020 10:30 am

By Jennifer Smith

A survey of gynecologic cancer survivors has revealed why some of these patients don’t participate in clinical trials.

Half of survey respondents with no history of trial participation said their medical team never mentioned the possibility of
Read more

Study Findings Support the Use of Video-Assisted Genetic Counseling in Ovarian Cancer

March 31, 2020 10:00 am

By Susan Moench, PhD, PA-C

Results of a randomized clinical trial evaluating video-assisted genetic counseling followed by either formal genetic counseling or direct referral for genetic testing in women with ovarian/fallopian/peritoneal cancer receiving adjuvant therapy showed that a significantly higher … Read more

New Research Shows Which Ovarian Cancer Patients Won’t Benefit From Immune-PARP Combo

March 19, 2020 10:10 am

BOSTON – In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions, clinical trials have shown, but up until now investigators haven’t been able to predict which patients … Read more

Pathogenic Variants in RAD51C and RAD51D Linked to Ovarian and Breast-Cancer Risk

March 7, 2020 10:00 am

By Will Boggs MD

NEW YORK (Reuters Health) – Pathogenic variants in RAD51C and RAD51D are associated with an increased risk of ovarian and breast cancer, researchers report.

“RAD51C and RAD51D are included in cancer gene panels that are widely … Read more

Family History of Heart Disease Makes Premature Removal of Ovaries Especially Risky

March 4, 2020 11:00 am

CLEVELAND, Ohio (March 4, 2020)–Women who proactively have their ovaries removed to minimize their cancer risk may face a greater risk–premature death because of heart disease. That’s according to a new study that identifies an increased risk for women with … Read more

Research Suggests Statins Could Lower Ovarian Cancer Risk

February 18, 2020 10:00 am

By Cancer Research UK

A genetic study has found evidence to suggest that women who take statins in the long term could be less likely to develop ovarian cancer, according to new research funded by Cancer Research UK published today … Read more

Simple Blood Test Measures the Body’s Immune Response to Improve Ovarian Cancer Diagnosis

February 17, 2020 10:00 am

Researchers have developed a simple blood test that measures the body’s own immune response to improve diagnosis of ovarian cancer.

Ovarian cancer is one of the most common gynecologic cancers, with the highest mortality rate. About 300,000 new cases are … Read more

Higher Risk of Ovarian Clear Cell Cancer in Asian Pacific Islanders

February 14, 2020 10:00 am

By Christina Bennett, MS

Regardless of birthplace, women who are Asian Pacific Islanders may have a higher risk of developing ovarian clear cell cancer compared with other ethnicities, according to a population-based retrospective cohort study. The findings were recently published … Read more

Psychedelic Mushrooms Can Help Ease Anxiety and Depression in Cancer Patients for Years, Scientists Believe

February 3, 2020 11:00 am

By Kashmira Gander

Taking a single dose of a psychedelic compound found in magic mushrooms can ease symptoms of anxiety and depression in cancer patients for years, according to a study.

Almost five years after taking the compound psilocybin while … Read more

Talc Powder Not Linked to Ovarian Cancer in Prospective Datasets

January 7, 2020 5:00 pm

By Ian Ingram

— With some 250,000 participants, study rules out all but smallest risk increases

New research on a quarter-million women from four U.S. cohorts found no significant association between ovarian cancer and the use of powder-based products in … Read more

Endometriosis Appears to Have No Effect on Ovarian Cancer Outcomes, But More Research Needed, Study Says

December 17, 2019 3:00 pm

By Marissa Wexler, MS

Endometriosis does not seem to significantly affect ovarian cancer prognosis and survival in patients of reproductive age, a small study suggests.

However, more research is needed to identify factors associated with the progression of endometriosis to … Read more

CA125 Test Detects Far More Ovarian Cancer Cases Than Thought

November 6, 2019 6:00 pm

By Liam Davenport

A blood test for detecting ovarian cancer is far more effective in the primary care setting than previously thought, say UK researchers, who suggest National Institute for Health and Care Excellence (NICE) guidelines will need to be … Read more

Genetically Definable Subgroups of Cancers Sensitive to Treatment

October 24, 2019 5:00 pm

Precision oncology aims to use genetic features of a patient’s tumor to tailor anti-cancer therapy. DNA mutations in a drug target have provided a number of therapeutic opportunities; however, there are many cancer types that do not have obvious targetable … Read more

‘Wild Idea’ Opens Possible New Frontier for Preventing Ovarian Cancer

October 9, 2019 3:00 pm

A laboratory study published in Clinical Cancer Research offers a new hypothesis about how ovarian cancer forms and suggests how it might be prevented.

The study is the first to show that the natural stiffening of the ovaries called fibrosis … Read more

Discovery of New “Don’t Eat Me Protein” Points the Way to Effective Cancer Therapy

August 1, 2019 4:00 pm

By Alexandru Micu

Stanford University (SU) researchers have found a new signaling molecule that cancer cells use to keep the immune system at bay.

Our bodies’ immune cells are, among other objectives, tasked with clearing out malfunctioning cells. In theory, … Read more

New Discovery Could Open Up PARP Inhibitors to More Cancer Patients

July 25, 2019 4:00 pm

By Amirah Al Idrus

PARP inhibitors have transformed treatment for breast and ovarian cancers, but their use has been limited to the small proportion of patients who have BRCA mutations. New research out of UT Southwestern Medical Center has uncovered … Read more