PARP Inhibitor Benefit Gets a TWiST in Recurrent Ovarian Cancer

March 17, 2019 6:00 pm

By Ian Ingram

In delaying disease progression in recurrent ovarian cancer, maintenance therapy with the PARP inhibitor niraparib (Zejula) also increased patients’ time without symptoms or toxicity (TWiST), an analysis of the phase III NOVA trial found.

Compared with placebo, … Read more

Cancer Biomarker for PARP Inhibitor Effectiveness Discovered

March 15, 2019 5:00 pm

Since tumors often have unique defects in the DNA damage response (DDR) pathway, identifying the molecular mechanisms that underlie how cells repair various DNA lesions is critical to selecting the appropriate clinical treatments. Inhibitors to poly-(ADP-ribose) polymerase (PARP) are examples … Read more

Ovarian Cancer Survivors Carry Burden of Severe Long-Term Fatigue

March 14, 2019 5:00 pm

By Will Pass

Women who have survived epithelial ovarian cancer (EOC) more often report severe long-term fatigue than healthy women, according to a case-control study involving more than 600 individuals.

Ovarian cancer survivors had a higher rate of sleep disturbance, … Read more

New Device Can Detect Cancer in Just a Drop of Blood

February 26, 2019 5:00 pm

By Maria Cohut

Some types of cancer, such as ovarian cancer, tend to remain undetected until they are too advanced for treatment to be effective. Now, an innovative tool may be able to detect cancer easily, quickly, and in minuscule … Read more

Could Conservative Management of Adnexal Masses Lead to Ovarian Cancer?

February 20, 2019 5:00 pm

By Dave Levitan

Conservative management of adnexal masses classified as benign was associated with a low risk of subsequent malignant ovarian cancer, according to a new study.

“Adnexal masses are often detected incidentally and most of them prove to be … Read more

AI Predicts Ovarian Cancer Survival Rates From CT Scans

February 15, 2019 5:00 pm

By Melissa Rohman

AI can predict a woman’s survival rate and response to treatments for ovarian cancer more accurately than current methods, according to research published online Feb. 15 in Nature Communications. 

The machine learning software developed by researchers at … Read more

Ovarian Cysts Should Be ‘Watched’ Rather Than Removed

February 5, 2019 5:00 pm

Women may not need to undergo surgery for non-cancerous ovarian cysts, avoiding potential surgical complications.

This is the finding of new research, by a team of international scientists from institutions including Imperial College London and KU Leuven, published in The Read more

Drug Treating Breast Cancer May Be Effective in Treating Lung and Ovarian Cancer

February 5, 2019 4:00 pm

Two new papers, published simultaneously in Nature Communications and led by researchers at McGill University, offer promise that a drug currently used to treat estrogen positive breast cancer may be effective in treating two different types of cancer, one rare … Read more

Drug Target Identified for Chemotherapy-Resistant Ovarian, Breast Cancer

February 4, 2019 5:00 pm
By Tamara Bhandari Study finds mimic for BRCA genes that could be targeted to improve treatment People who inherit a faulty copy of the so-called “breast cancer genes” BRCA1 and BRCA2 are at high risk of cancer. About 10 percent… Read more

Energizing the Immune System to Eat Cancer

January 21, 2019 3:00 pm

Immune cells called macrophages are supposed to serve and protect, but cancer has found ways to put them to sleep. Now researchers at the Abramson Cancer Center of the University of Pennsylvania say they’ve identified how to fuel macrophages with … Read more

AI Tool Scans Tumour Shape to Detect Aggressive Ovarian Cancer

January 15, 2019 12:30 am

Researchers at The Institute of Cancer Research, London (ICR) have developed an artificial intelligence (AI) test that analyses the shape of tumour cells to identify patients with aggressive ovarian cancer.

The test is intended to enable tailored treatment based on … Read more

Palliative Care May Improve Survival, Quality of Life in Advanced Cancer

January 14, 2019 5:30 pm
By Brielle Benyon Recent research found that outpatient palliative care improved survival and quality of life in patients with advanced cancer. Palliative care may boost survival in patients with advanced cancer, according to recent research conducted at Tulane University. “If… Read more

PCOS May Increase Overall Cancer Risk

December 13, 2018 5:00 pm

By Regina Schaffer

Swedish women with polycystic ovary syndrome are 15% more likely to develop any cancer vs. women without the condition, with risk further elevated for cancers of the endometrium, ovary, pancreas and kidney, according to a research letter … Read more

Cancer DNA Binds to Gold. That Could Lead to New Cancer Blood Test.

December 5, 2018 7:30 pm

By Rachael Rettner, Senior Writer

Researchers have discovered a curious difference between the DNA from cancer cells and that from healthy cells, and this finding could lead to a new blood test for cancer.

The difference? Cancer DNA has a … Read more

Sound and Light Could Detect Ovarian Cancer Earlier

November 23, 2018 11:32 pm

By Beth Miller

Researchers have found an innovative way to use sound and light, or photoacoustic, imaging to diagnose ovarian tumors. The method may lead to a promising new diagnostic imaging technique to improve current standard of care for patients Read more

Ultrasonography Useful for Predicting Ovarian Cancer Risk

November 21, 2018 9:55 pm

By Will Boggs MD

The ultrasonographic appearance of ovarian masses is strongly associated with a woman’s risk of ovarian cancer, researchers report.

“Ovarian cancer is a frightening and devastating disease, and we want to be able to find ovarian cancer … Read more

New Dual-Action Cancer-Killing Virus

November 18, 2018 8:00 pm

Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system.

It is the first time that cancer-associated fibroblasts … Read more

Ultrasound Finds Simple Cysts Not Associated With Ovarian Cancer Risk

November 13, 2018 3:00 pm

By Melissa Rohman

Using ultrasound technology, researchers found simple ovarian cysts—commonly found amongst premenopausal and postmenopausal women—are not associated with an increased risk of ovarian cancer and do not require additional surveillance or surgical intervention, according to research published online

Read more

Open Source Tool Predicts Chemo Drugs Best Suited for Individual Patients

November 12, 2018 12:09 am

Researchers at Georgia Institute of Technology (Georgia Tech) have developed a new open-source decision support tool designed to help clinicians chose the chemotherapy drug best suited for individual patients.

The open-source support vector machine (SVM)-based algorithm predicted the chemotherapy drug … Read more

Ovarian Cancer Risk Reduced with Postmenopausal Statins

November 7, 2018 5:00 pm

By Pam Harrison

All histologic types of ovarian cancer risk lowered in statin versus non-statin users.

Women who started taking a statin at the age of 50 or older had a significantly lower risk of developing any histologic type of … Read more