How ovarian cancers evade the immune system

October 6, 2021 12:00 am

By Krista Conger

It’s diabolical, and so clever. Recent research by cancer biologist Wendy Fantl, PhD, and immunologist and cancer biologist Veronica Gonzalez, PhD, shows that ovarian tumors thrive by convincing nearby immune cells that the cancer cells are those … Read more

Women with genetic mutations fare no worse with breast or ovarian cancer, study finds

October 1, 2021 12:00 am

By Krista Conger

Newly diagnosed breast or ovarian cancer patients who carry common cancer-associated mutations have similar or better short-term survival rates than those with no mutations, researchers report.

Women newly diagnosed with breast or ovarian cancer who are also … Read more

Third COVID Vaccine Dose Boosts Protection in Solid Tumor Patients

October 1, 2021 12:00 am

By Mike Bassett

— For those on active therapy, 80% had increased antibody levels, study showed

A third dose of Pfizer’s COVID-19 vaccine (BNT162b2; Comirnaty) could offer increased protection for cancer patients on active treatment, a new study suggested, as … Read more

What Patients With Ovarian Cancer Should Know About Maintenance Therapy

September 29, 2021 10:05 am

By Jamie Cesanek

Maintenance therapy is meant to prevent relapse after a patient with ovarian cancer received their main treatment. Here’s an overview of what patients should know.

When a patient is diagnosed with ovarian cancer, their initial treatment typically

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Symptoms of Ovarian Cancer Explained as Woman Diagnosed Thanks to Small Navel Growth

September 28, 2021 12:00 am

By Aatif Sulleyman

A woman is raising awareness of ovarian cancer and how difficult it can be to detect, having been diagnosed with the illness by a dermatologist who removed a small growth from her navel.

Despite being aware of … Read more

Wistar Scientists Identify New Therapeutic Target in Ovarian Cancer Subtype With Poor Prognosis. Ovarian clear cell carcinomas with ARID1A mutations are sensitive to inhibition of the IRE1a-XBP1 stress response pathway in preclinical models.

September 21, 2021 5:12 pm

By Wistar Institute

Newswise — PHILADELPHIA — (Sept. 21, 2021) — Mutations in the ARID1A gene are present in more than 50% of ovarian clear cell carcinomas (OCCC), for which effective treatments are lacking. Scientists at The Wistar Institute discovered … Read more

Two Pathways, One Destination: Promising Drug Combination to Treat Ovarian Cancer

March 15, 2021 3:00 pm

By R. Colon-Thillet

Treatment for ovarian cancer across subtypes typically consists of platinum-based chemotherapies. However, this standard therapy is less effective against ovarian clear cell carcinoma (OCCC), a rare subtype of ovarian cancer with distinct pathology and genetic drivers. Advanced … Read more

FDA Grants Priority Review to Pafolacianine Sodium Injection in Ovarian Cancer

March 3, 2021 4:00 pm

The FDA has granted priority review to the new drug application for the novel compound pafolacianine sodium injection for use in the identification of ovarian cancer during surgery.

By Courtney Marabella

The FDA has granted priority review to the new

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Most Patients With Breast, Ovarian Cancer Patients Do Not Undergo Genetic Testing

March 1, 2021 7:00 pm

By Christina Bennett, MS

The number of genes tested for ovarian and breast cancer has grown in recent years, but most patients do not undergo testing.  Thus, variant-of-unknown-significance (VUS) results are common, especially among minority populations, according to the results … Read more

Clearity Caregiver’s Week – Denise and Michelle’s Story

February 21, 2021 6:00 pm

Eleven years ago, my wife and I had the rug pulled out from under us. Michelle was diagnosed with ovarian cancer, and we were thrust into a new, alien world—Michelle as patient, and me as caregiver—a role I frankly wasn’t … Read more