Patients with BRCA1/2 mutations are at higher risk for breast, ovarian and prostate cancers that can be aggressive when they develop—and, in many cases, resistant to lifesaving drugs. Now scientists at The University of Texas at Austin and Ajou University … Read more
A recent finding by researchers at UBC’s faculty of medicine and the BC Cancer Research Institute (BCCRI) may offer a new treatment possibility for people diagnosed with a rare and aggressive form of ovarian cancer.
Small cell carcinoma of the … Read more
A Scripps Research team reports the discovery of a molecule that can activate a natural immune-boosting protein called STING. The findings mark a key advance in the field of oncology, as the STING protein is known for its strong antitumor … Read more
A global team of medical researchers led by UNSW have developed a test that could help to predict survival for women diagnosed with ovarian cancer, and pave the way towards personalised treatment.
A tumour test could help to identify ovarian … Read more
Women who underwent chemotherapy or surgery for gynecologic cancer and also had COVID-19 infection did not appear at significantly increased risk for death due to the novel coronavirus, according to study findings published in Cancer.
However, recent immunotherapy use … Read more
The cover for issue 29 of Oncotarget features, “In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model,” by Lara, et al. which reported that adaptor proteins such as growth factor … Read more
These results suggest the need for future studies to examine scalable interventions to improve fatigue in women with gynecologic cancers.
By Hannah Slater
A 1-year longitudinal study published in Cancer suggested that almost half of women with gynecologic cancers had
By Diana Swift
Population screening found to be cost-effective for higher income countries
Screening entire populations of women for mutations in breast and ovarian cancer susceptibility genes could prevent hundreds of thousands of cases in the U.S., and millions globally, … Read more
Ten percent of women who received a hysterectomy and salpingectomy, or removal of the fallopian tubes, during the study period had a family history of breast or ovarian cancer.
By Ryan McDonald
Despite limited data to support its use, the … Read more
A novel blood test accurately detected more than 50 types of cancer with a specificity of 99.3%.
By Mark Leiser
A novel blood test accurately detected more than 50 types of cancer with a specificity of 99.3%, according to results … Read more
A drug known as SP-2577 could help enable the body’s own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.
Published today in the scientific … Read more
According to new research published in Clinical and Translational Immunology, a new cancer vaccine is ready for human trials following its success in preclinical studies.
By Alana Hippensteele
The vaccine was recently developed by a research team based at The … Read more
High-grade serous epithelial ovarian cancer may be detected earlier in the course of the disease by testing for TP53 clonal variants in DNA from Pap tests.
By Leah Lawrence
High-grade serous epithelial ovarian cancer may be detected earlier in the … Read more
In cell and mouse models, miR-181a showed promise as a biomarker for early stage ovarian cancer and may help make immunotherapy treatment more effective.
By Ian Demsky
A microRNA that is normally involved in immune cell differentiation helps to initiate
A study presented at the AACR Virtual Annual Meeting II showed a significant decrease in mortality rate for patients with epithelial ovarian cancer when treated with lipophilic statins, supporting the further evaluation of statins to treat ovarian cancer in randomized … Read more
Inhibiting the JAK/STAT pathway could represent a potential treatment for high-grade serous ovarian cancer, according to a single-cell analysis.
Researchers led by the Broad Institute’s Aviv Regev used single-cell RNA sequencing (scRNA-seq) to analyze about 11,000 cells from ascites from … Read more