CA125 Test Detects Far More Ovarian Cancer Cases Than Thought

November 6, 2019 6:00 pm

By Liam Davenport

A blood test for detecting ovarian cancer is far more effective in the primary care setting than previously thought, say UK researchers, who suggest National Institute for Health and Care Excellence (NICE) guidelines will need to be … Read more

Genetically Definable Subgroups of Cancers Sensitive to Treatment

October 24, 2019 5:00 pm

Precision oncology aims to use genetic features of a patient’s tumor to tailor anti-cancer therapy. DNA mutations in a drug target have provided a number of therapeutic opportunities; however, there are many cancer types that do not have obvious targetable … Read more

‘Wild Idea’ Opens Possible New Frontier for Preventing Ovarian Cancer

October 9, 2019 3:00 pm

A laboratory study published in Clinical Cancer Research offers a new hypothesis about how ovarian cancer forms and suggests how it might be prevented.

The study is the first to show that the natural stiffening of the ovaries called fibrosis … Read more

UCSD Researchers Find FAK Protein Linked to Chemotherapy Resistance in Ovarian Cancer

September 12, 2019 5:00 pm

Although the number of women being diagnosed and dying of ovarian cancer is declining, recurrence, drug resistance, and mortality remains high for women with high-grade serous ovarian carcinoma, the most common form of epithelial ovarian cancer. 

A new study in Read more

Rare Ovarian Cancer Confirmed as Not Seeded from Elsewhere

September 6, 2019 5:15 pm

By Peter MacCallum

An international study led by Peter Mac has revealed the origin of mucinous ovarian cancer (MOC) confirming, unlike other types of ovarian cancer, this rare cancer is not seeded from elsewhere in the body.

The research provides … Read more

Researchers Develop Early Detection Test for Ovarian Cancer

August 23, 2019 5:00 pm

Researchers from Queen’s University Belfast have developed a test that may be able to detect ovarian cancer up to two years earlier than current approaches.

The researchers discovered that the presence of four proteins together, known as a biomarker panel, … Read more

Ovarian Cancer: Is this the Beginning of the End?

August 10, 2019 6:00 pm

By Michael J. Birrer, MD, PhD

There will be 22,530 new cases of ovarian cancer in the United States this year.

Although tumors often present at an advanced stage, it remains one of the most chemosensitive epithelial cancers, with a … Read more

BRCA Mutation, Preventive Surgery, and Osteoporosis

August 8, 2019 4:00 pm

By Kristen Monaco

Researchers advocate for increased hormone therapy for high-risk women.

Bone health suffered in women with a BRCA mutation who underwent preventive oophorectomy, Canadian researchers reported.

Premenopausal women with the BRCA1 or BRCA2 mutation experienced a significant decline … Read more

Germline BRCA2 Mutations Linked to Pediatric Lymphomas

August 2, 2019 5:00 pm

By Leah Lawrence

In addition to putting carriers at increased risk for breast and ovarian cancers, BRCA2 germline mutations carriers are also at increased risk for pediatric and adolescent non-Hodgkin lymphoma (NHL), according to data from the SJLIFE study.… Read more

Discovery of New “Don’t Eat Me Protein” Points the Way to Effective Cancer Therapy

August 1, 2019 4:00 pm

By Alexandru Micu

Stanford University (SU) researchers have found a new signaling molecule that cancer cells use to keep the immune system at bay.

Our bodies’ immune cells are, among other objectives, tasked with clearing out malfunctioning cells. In theory, … Read more

New Discovery Could Open Up PARP Inhibitors to More Cancer Patients

July 25, 2019 4:00 pm

By Amirah Al Idrus

PARP inhibitors have transformed treatment for breast and ovarian cancers, but their use has been limited to the small proportion of patients who have BRCA mutations. New research out of UT Southwestern Medical Center has uncovered … Read more

Targeting a Key Protein May Keep Ovarian Cancer Cells from Spreading

July 15, 2019 12:50 pm

By Zachary Sweger

Preventing a protein from doing its job may keep a certain type of ovarian cancer cell from growing and dividing uncontrollably in the lab, according to a new study from Penn State College of Medicine.

In … Read more

Ovarian Cancer and Bacteria in the Vagina: A New Study Found a Link, So We Asked the Experts What Women Need to Know

July 11, 2019 7:00 am

By Caroline Hopkins

The study found that younger women (under 50) with ovarian cancer had lower levels of “good bacteria” in their vaginas than women who were cancer-free. But the experts said we shouldn’t draw any conclusions about cancer risk Read more

Novel Ovarian Cancer Diagnostic May Eliminate Need for Exploratory Surgery

June 21, 2019 6:00 pm

Scientists at Uppsala University and the Sahlgrenska Academy, University of Gothenburg say they have developed a blood test that may provide a more precise diagnostic for suspected ovarian cancer that would eliminate the need for exploratory surgery. This could lead … Read more

Research Shows How Talc Powder May Change Ovarian Cancer Cells

June 18, 2019 6:00 pm

By Sarah Elizabeth Richards

Does talc cause cancer? At least 13,000 people think so, and have filed lawsuits against Johnson & Johnson, the manufacturer of several talcum-based products. Yet so far, juries and scientists have been divided on the … Read more

Novel Treatment Turns Tumors Into ‘Cancer Vaccine Factories’

June 13, 2019 5:00 pm

By Mark L. Fuerst

In-situ vaccine may enhance immunotherapy response in resistant cancers, study shows.

A novel approach to cancer immunotherapy injects immune stimulants directly into a tumor to “teach,” induce the immune system to destroy the cancer and other

Read more

Scientists Uncover Mechanism of Action for Promising Cancer Compound

June 5, 2019 5:00 pm

University of North Carolina Lineberger Comprehensive Cancer Center researchers have uncovered the mechanism that explains how an investigational cancer therapeutic might be working—a finding that they believe could be important for the design of potential new therapies.

In the journal … Read more

Medicaid Expansion Narrows Racial Gaps in Access to Timely Ovarian Cancer Care

June 4, 2019 5:00 pm

by Paige Minemyer

Medicaid expansion may have significantly reduced racial disparities in access to earlier ovarian cancer treatment, according to a new study.

The findings, which were presented at the American Society of Clinical Oncology’s annual meeting, show that … Read more

ACA May Impact Ovarian Cancer Outcomes

June 2, 2019 5:00 pm

By John Schieszer

Under the Affordable Care Act (ACA), women with ovarian cancer were more likely to be diagnosed at an early stage and receive treatment within 30 days of diagnosis, according to researchers at Johns Hopkins School of Medicine, … Read more

CRISPR Reveals New Cancer Drug Targets through ID of Critical Gene Fusion Regions

May 16, 2019 6:00 pm

In what they claim is the first large-scale systematic analysis of thousands of gene fusions in human cancers, scientists have identified a gene fusion that could represent a novel drug target for multiple cancers. Through their studies, the largely U.K.-based … Read more