Imaging System Helps Surgeons Remove Tiny Ovarian Tumors

April 23, 2019 5:00 pm

By Anne Trafton

More effective surgery could boost survival rates for ovarian cancer.

Ovarian cancer is usually diagnosed only after it has reached an advanced stage, with many tumors spread throughout the abdomen. Most patients undergo surgery to remove as

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Smart Nanoparticles Help Improve Treatment of Peritoneal Tumors

April 22, 2019 5:00 pm

Research carried out at the University of Tartu Faculty of Medicine used nanoparticles for the development of new imaging and treatment methods for peritoneal cancers. Tests showed that precision-guided anticancer nanoparticles have improved efficacy and reduced side effects.

One of … Read more

Social Media Posts Identify Needs, Concerns of Patients with Ovarian Cancer

April 18, 2019 5:00 pm

By Beth Fand Incollingo and Kristie L. Kahl

Patients with ovarian cancer tend to underreport their most challenging symptoms; however, an analysis of their online comments could give health care providers insight into how to help.

A machine learning approach … Read more

Ovarian Cancer Patients Undertested for Mutations that Could Guide Clinical Care

April 9, 2019 4:00 pm

By Krista Conger

A large study of women with breast and ovarian cancer has revealed significant gaps between national guidelines for genetic testing and actual testing practices, according to researchers from Stanford and five other institutions.

Fewer than a quarter … Read more

Study: Birth Control Pills Protect Against Aggressive Ovarian Cancer

April 3, 2019 5:00 pm

“The longer the history of oral contraceptive use, the greater the protection we observed in terms of reduced chance of dying from aggressive ovarian cancer,” said study first author Jennifer Mongiovi.

The protection that birth control pills offer against ovarian … Read more

SGO 2019: Less Worry, More Symptoms and Regret With Risk-Reducing Salpingo-Oophorectomy

March 20, 2019 5:00 pm

By Christina Bennett, MS

Women at increased risk for hereditary ovarian cancer who underwent risk-reducing salpingo-oophorectomy experienced less worry but worse menopausal symptoms and more regret compared with those who underwent salpingectomy with delayed oophorectomy, the Women Choosing Surgical Prevention … Read more

New Class of Drugs Could Treat Ovarian Cancer

March 19, 2019 5:00 pm

A team of researchers across The University of Manchester have shown that a new class of drugs are able to stop ovarian cancer cells growing.

The Cancer Research UK and Wellcome Trust funded study, published in the journal Cancer CellRead more

Individualized Dosing Regimen Reduces Side Effects in Ovarian Cancer Maintenance Therapy

March 18, 2019 7:00 pm

By Kristie L. Kahl

Side effects decreased among patients with high-risk ovarian cancer who received an individualized starting dose of Zejula (niraparib), based upon baseline bodyweight and platelet counts, compared with a fixed starting dose, according to a recent analysis

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When PARP Inhibitors Fail in Ovarian Cancer

March 18, 2019 6:00 pm

By Ian Ingram

Study identifies subgroup for whom another go could be worthwhile.

Lack of response to a PARP inhibitor in epithelial ovarian cancer didn’t necessarily mean patients were resistant to all such agents, a small retrospective study indicated.

Among … Read more

PARP Inhibitor Benefit Gets a TWiST in Recurrent Ovarian Cancer

March 17, 2019 6:00 pm

By Ian Ingram

In delaying disease progression in recurrent ovarian cancer, maintenance therapy with the PARP inhibitor niraparib (Zejula) also increased patients’ time without symptoms or toxicity (TWiST), an analysis of the phase III NOVA trial found.

Compared with placebo, … Read more

Cancer Biomarker for PARP Inhibitor Effectiveness Discovered

March 15, 2019 5:00 pm

Since tumors often have unique defects in the DNA damage response (DDR) pathway, identifying the molecular mechanisms that underlie how cells repair various DNA lesions is critical to selecting the appropriate clinical treatments. Inhibitors to poly-(ADP-ribose) polymerase (PARP) are examples … Read more

Ovarian Cancer Survivors Carry Burden of Severe Long-Term Fatigue

March 14, 2019 5:00 pm

By Will Pass

Women who have survived epithelial ovarian cancer (EOC) more often report severe long-term fatigue than healthy women, according to a case-control study involving more than 600 individuals.

Ovarian cancer survivors had a higher rate of sleep disturbance, … Read more

Targeting Stem-Like Cells Could Prevent Ovarian Cancer Recurrence

March 12, 2019 5:00 pm

Ovarian cancer is not the most common form of cancer, but it’s among the deadliest. That’s because about 70 percent of cases recur. A new study by researchers at the University of Pittsburgh, UPMC Hillman Cancer Center, Magee-Women’s Research Institute … Read more

Lymphadenectomy Found Not Beneficial in Advanced Ovarian Cancer

March 7, 2019 3:00 pm

By Susan Moench

The results from the Lymphadenectomy in Ovarian Neoplasms (LION) trial, published in the New England Journal of Medicine, which compared systematic pelvic and paraaortic lymphadenectomy with no lymphadenectomy in some women with advanced ovarian cancer, showed … Read more

New Device Can Detect Cancer in Just a Drop of Blood

February 26, 2019 5:00 pm

By Maria Cohut

Some types of cancer, such as ovarian cancer, tend to remain undetected until they are too advanced for treatment to be effective. Now, an innovative tool may be able to detect cancer easily, quickly, and in minuscule … Read more

Could Conservative Management of Adnexal Masses Lead to Ovarian Cancer?

February 20, 2019 5:00 pm

By Dave Levitan

Conservative management of adnexal masses classified as benign was associated with a low risk of subsequent malignant ovarian cancer, according to a new study.

“Adnexal masses are often detected incidentally and most of them prove to be … Read more

AI Predicts Ovarian Cancer Survival Rates From CT Scans

February 15, 2019 5:00 pm

By Melissa Rohman

AI can predict a woman’s survival rate and response to treatments for ovarian cancer more accurately than current methods, according to research published online Feb. 15 in Nature Communications. 

The machine learning software developed by researchers at … Read more

New ‘Trojan Horse’ Cancer Treatment Shows Early Promise in Multiple Tumor Types

February 8, 2019 9:00 am

A brand new type of cancer drug that acts as a ‘Trojan horse’ to get inside tumour cells has shown promise in patients with six different cancer types.

In patients with advanced, drug-resistant cancers, over a quarter with cervical and … Read more

The First-Ever Clinical Trial Using Tocotrienols with Ovarian Cancer Patients, Increased their Survival by Seventy Percent in Refractory Ovarian Cancer

February 7, 2019 3:00 pm

A recent study conducted at Denmark’s Vejle Hospital, published in Pharmacological Research, provides evidence of delta-tocotrienol’s benefits for cancer patients. Results of the open-label trial suggest that American River Nutrition-manufactured delta-tocotrienol in combination with bevacizumab had additive effects in chemotherapy … Read more

Ovarian Cysts Should Be ‘Watched’ Rather Than Removed

February 5, 2019 5:00 pm

Women may not need to undergo surgery for non-cancerous ovarian cysts, avoiding potential surgical complications.

This is the finding of new research, by a team of international scientists from institutions including Imperial College London and KU Leuven, published in The Read more