BRCA1 Methylation Tied to Ovarian Cancer Risk

January 18, 2018 4:26 am

BRCA1 mutations are well-known to predispose to ovarian cancer risk. But now a new study, appearing in the Annals of Internal Medicine, suggests that methylation of normal BRCA1 genes might be a major ovarian cancer risk factor. In this Read more

Heated Abdominal Chemo Bath Improves Ovarian Cancer Survival

January 17, 2018 5:00 pm

By Gene Emery

A heated chemotherapy organ bath circulated throughout the abdomen after surgery can significantly prolong a woman’s survival with advanced ovarian cancer, according to doctors testing the new treatment.

Patients who underwent the experimental procedure at 8 hospitals … Read more

Women with Ovarian Cancer Who May Benefit from Maintenance Treatment

January 15, 2018 6:18 pm

Myriad Genetics and AstraZeneca have expanded their collaboration to conduct a study to identify women with advanced ovarian cancer who may benefit from maintenance treatment with Lynparza (olaparib) and Avastin (bevacizumab).

Myriad’s myChoice HRD Plus is a test for BRCA1 … Read more

Combinations May Be The Future Of Immunotherapy In Ovarian Cancer

January 12, 2018 10:27 pm

To date, trials testing the use of immunotherapy in the treatment of ovarian cancer yielded disappointing results. However, researchers are not giving up. Instead, they’re investigating to see if immunotherapy drugs – such as PD1 and PDL-1 inhibitors – can … Read more

Foundation For Women’s Cancer Fights To End Clinical Trial Crisis

January 10, 2018 6:36 pm

When Wendy Ericsson learned she had uterine cancer in December 2012 she went looking for information, but didn’t find much out there about her disease.

Through her doctor, she was directed to the Foundation for Women’s Cancer (FWC).

“There’s a … Read more

With Cancer, Timing Is Everything

January 8, 2018 10:41 pm

I had a family member who was diagnosed with late stage ovarian cancer 20 years ago and died of the disease at the age of 47. Even though her symptoms appeared a year before her diagnosis with abdominal bloating, indigestion, … Read more

7 Key Cancer Trends For 2018

January 3, 2018 6:48 pm

By: Elaine Schattner

I expect progress. Here’s my list of major trends and issues that will affect the lives of cancer patients in 2018:

1. Less chemotherapy

recent report finds that among patients with the most common form of … Read more

FDA Grants Priority Review for Rucaparib

December 28, 2017 8:08 pm

The US Food and Drug Administration (FDA) has granted priority review status to rucaparib as maintenance therapy for women with recurrent ovarian cancer, according to the drug’s developer. The application is for women who are platinum sensitive, and in complete … Read more

Immortality at Midnight

December 22, 2017 7:57 pm

By: Susan Gubar

Toward the end of another unexpected year of existence, outliving a poor prognosis of late-stage cancer rouses me in the dark. Such an awakening is quite different from the fretful insomnia that accompanied the dire diagnosis. Especially … Read more

Fallopian Tube Removal May Help Prevent Most Common Ovarian Cancer

December 20, 2017 7:52 pm

A study published in October showed that high-grade serous ovarian carcinomas (HGSOC), which account for about 75 percent of ovarian cancers, originate with abnormal cells in the fallopian tubes an average of seven years before the disease develops. This understanding … Read more

Self-Image And Cancer: Seeing The New, Better You

December 18, 2017 8:48 pm

By: Kelly Irvin

No matter how cancer makes you look, you’re still you—a better you.

It sounds like an obvious statement. But cancer wrecks physical havoc on our bodies, which affects our self-images. I state this for the record because … Read more

Future Focus: Ovarian Cancer in 2018 and Beyond

December 14, 2017 3:49 pm

Oliver Dorigo, M.D., Ph.D., Associate Professor of Obstetrics and Gynecology (Oncology), Stanford University Medical Center, talks about the direction of research in the ovarian cancer field going into 2018 and beyond. He shares his excitement about trials that will further … Read more

Health Matters: Testing Your Genes for Cancer

December 12, 2017 12:21 am

Whether you’ve already been diagnosed, or you want to know your risk, health experts can test your DNA to determine your chances of developing cancer.

“The testing itself determines whether or not they have inherited this broken gene that could … Read more

Tumor Profiling Panel Undergoes Simultaneous FDA, CMS Review

December 9, 2017 12:04 am

The US Food and Drug Administration (FDA) has approved a cancer diagnostic test, FoundationOne CDx (F1CDx, Foundation Medicine), for use in detecting 300-plus genetic mutations in any solid tumor. At the same time, the Centers for Medicare & Medicaid Services … Read more

An Ovarian Cancer Survivor’s Holiday Wish List

December 6, 2017 3:52 pm

By: Annette McElhiney

Now that it is December, most of us are preparing for the holidays. We plan and host parties, we prepare special foods, we give presents, and we create a “wish list” for ourselves. I’ve said many times … Read more

Immunotherapy Has Big Potential In Ovarian Cancer Treatment

November 27, 2017 8:50 pm

Early studies are showing promise for immunotherapy agents such as checkpoint inhibitors in the treatment field of ovarian cancer, according to Jonathan Ledermann, M.D.

One such study is JAVELIN Ovarian 200, a study of Bavencio (avelumab) alone or in combination … Read more