‘Devastated and Sad’ After 36 Years of Research — Early Detection of Ovarian Cancer Doesn’t Save Lives

May 19, 2021 1:00 pm

By Professor Ian Jacobs

I was motivated to improve the outcome for women with ovarian cancer by my experience as a junior doctor in London in 1985. But 36 years on, the results aren’t what we’d hoped.

My colleages’ and

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Disappointment: Screening for Ovarian Cancer Does Not Cut Deaths

May 13, 2021 12:00 pm

By Pam Harrison

Results from a huge British trial that involved more than 200,000 women who were followed for a median of 16 years have turned out negative. Investigators found that annual screening for ovarian cancer with either multimodal screening … Read more

Cancer Patients Shouldn’t Let Imaging Concerns Delay COVID-19 Vaccine

March 3, 2021 7:00 pm

By Lisa Rapaport

Patients with cancer shouldn’t delay COVID-19 vaccination despite the potential for clinically evident adenopathy on imaging done after vaccination, according to recommendations from a multidisciplinary panel of scientific experts.

Vaccination-associated adenopathy or axillary swelling may appear within … Read more

Pap Test/Cervical Swab Samples Can Reveal Ovarian Cancer Biomarkers

February 22, 2021 10:00 am

 Sharon Worcester

Residual fixatives from liquid-based Pap tests and cervical swabs contain tumor-specific biomarkers for ovarian cancer, according to an analysis of proteins found in matched biospecimens from a woman with high grade serous ovarian cancer.

The findings suggest … Read more

Common Genetic Test Often Wrong When Identifying Rare Disease-Causing Variants Such as BRCA1 and BRCA2, Study Says

February 16, 2021 10:00 am

By Sandee LaMotte, CNN

A genetic test used to detect common traits many people share is not reliable in identifying rare disease-causing variations, such as those that can predict breast and ovarian cancer, a new study has found.

The SNP … Read more

If You Feel Something, Say Something

July 28, 2020 5:00 pm

Have you ever had a doctor roll his or her eyes or give you the brushoff after mentioning a health concern? If you’re like many women, it may not have been your imagination. As more and more research comes out … Read more

Universal BRCA Testing Could Prevent Countless Cancer Deaths

July 17, 2020 1:00 pm

By Diana Swift

Population screening found to be cost-effective for higher income countries

Screening entire populations of women for mutations in breast and ovarian cancer susceptibility genes could prevent hundreds of thousands of cases in the U.S., and millions globally, … Read more

Ovarian Cancer Metastasis Study Identifies Important Protein with Potential as Diagnostic Tool and Treatment Option

July 16, 2020 3:00 pm

By Clayton Boldt, Ph.D

Advanced ovarian cancer most commonly metastasizes to the omentum, a layer of fatty tissue that wraps around and protects internal organs in the abdomen, but the reasons for this have not been well-understood. In a new … Read more

Blood Test Detects Dozens of Cancer Types, Often Before Symptoms Emerge

July 13, 2020 5:00 pm

A novel blood test accurately detected more than 50 types of cancer with a specificity of 99.3%.

By Mark Leiser

A novel blood test accurately detected more than 50 types of cancer with a specificity of 99.3%, according to results … Read more

Pap Tests May Hold Biomarkers Ahead of Ovarian Cancer Diagnosis

July 10, 2020 4:00 pm

High-grade serous epithelial ovarian cancer may be detected earlier in the course of the disease by testing for TP53 clonal variants in DNA from Pap tests.

By Leah Lawrence

High-grade serous epithelial ovarian cancer may be detected earlier in the … Read more

New Test Paves the Way for Tailored Treatment of Deadliest Form of Ovarian Cancer

June 18, 2020 4:00 pm

University of British Columbia (UBC) researchers have led an international team in developing a new test to better diagnose different types of ovarian cancer, a tool that could one day guide and improve treatment options for women diagnosed with the … Read more

Convenient Spit Test Helps Women Assess Cancer Risk From The Comfort Of Their Own Homes

June 1, 2020 4:00 pm

By Stand Up To Cancer

Genetic testing for cancer risk can significantly improve the prevention or treatment of hereditary cancers, but studies have shown that people who might have a genetic risk often don’t get tested. A collaborative Stand Up … Read more

Blood Test Helped Detect Cancer Before Symptoms, Study Finds

April 28, 2020 10:45 am

by Marilynn Marchione

For the first time, a blood test has been shown to help detect many types of cancer in a study of thousands of people with no history or symptoms of the disease.

The test is still experimental. … Read more

AACR 2020: Cell-Free DNA Liquid Biopsy May Provide an Early Detection Test for Patients With Suspected Cancer

April 28, 2020 10:30 am

By Jo Cavallo

The Circulating Cell-free Genome Atlas Study is a large multicenter, case-controlled, observational study of 15,254 participants, 56% with cancer and 44% without cancer, with longitudinal follow-up to support the development of a cell-free DNA (cfDNA) multicancer early … Read more

CA125 Test Detects Far More Ovarian Cancer Cases Than Thought

November 6, 2019 6:00 pm

By Liam Davenport

A blood test for detecting ovarian cancer is far more effective in the primary care setting than previously thought, say UK researchers, who suggest National Institute for Health and Care Excellence (NICE) guidelines will need to be … Read more

Researchers Develop Early Detection Test for Ovarian Cancer

August 23, 2019 5:00 pm

Researchers from Queen’s University Belfast have developed a test that may be able to detect ovarian cancer up to two years earlier than current approaches.

The researchers discovered that the presence of four proteins together, known as a biomarker panel, … Read more

Novel Ovarian Cancer Diagnostic May Eliminate Need for Exploratory Surgery

June 21, 2019 6:00 pm

Scientists at Uppsala University and the Sahlgrenska Academy, University of Gothenburg say they have developed a blood test that may provide a more precise diagnostic for suspected ovarian cancer that would eliminate the need for exploratory surgery. This could lead … Read more

The CA125 Blood Test: Your Questions Answered

June 10, 2019 5:00 pm

What is a CA125 blood test?

CA125 is a protein that both men and women have in their blood. The normal level of this is 35 units per millilitre (U/mL), or lower.

A CA125 blood test is used to check … Read more

Epithelial Ovarian Cancer: BRCA Mutations, Brain Mets, and Breastfeeding

May 6, 2019 5:00 pm

By Kristin Jenkins

The presence of a BRCA germ line mutation in patients with invasive epithelial ovarian cancer may confer a short-term survival advantage, but is not associated with a reduction in long-term mortality, researchers found.

A follow-up study comparing … Read more

23andMe DTC Breast and Ovarian Cancer Risk Test Misses Almost 90 Percent of BRCA Mutation Carriers

April 5, 2019 5:00 pm

By Julia Karow

A study led by researchers at Invitae has found that 23andMe’s direct-to-consumer BRCA test, which tests for three common variants in the BRCA1 and BRCA2 genes and is authorized by the US Food and Drug Administration, misses … Read more