Taking A Wider View Of Precision Oncology

August 6, 2018 11:06 pm

Proponents of precision medicine cite the growing numbers of successful precision cancer drugs. The examples of Herceptin (trastuzumab), Gleevec (imatinib mesylate), Xalkori (crizotinib), and Zelboraf (vemurafenib) come to mind. Skeptics, on the other hand, focus on the … Read more

Quality of Life Maintained With Niraparib for Ovarian Cancer

August 1, 2018 9:19 pm

by Madeline Marr

The use of niraparib in women receiving treatment for platinum-sensitive recurrent ovarian cancer did not adversely affect quality of life (QoL), according to a study published in The Lancet Oncology.

An international team of researchers led … Read more

Treating Ovarian Cancers by Targeting Mutations

July 31, 2018 11:22 pm

New research has shown that ovarian cancer patients with a tumor mutation in the BRAF gene respond exceptionally well to treatment with targeted drugs, known as BRAF inhibitors.

BRAF inhibitors block the activity of mutated BRAF gene. They are currently … Read more

Low-Dose Aspirin May Help Against Ovarian Cancer

July 27, 2018 1:12 am
By Steven Reinberg
One low-dose aspirin a day could help women avoid ovarian cancer or boost their survival should it develop, two new studies suggest.

In fact, daily low-dose aspirin — the type many older women already take to help

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Cramps or Cancer: Elevated Menstrual Pain May be Associated with Ovarian Cancer Risk

July 24, 2018 7:10 pm

BY Brielle Urciuoli

Menstrual pain is something that, unfortunately, many women will encounter at some point during their lives. However, according to a recent study published in the International Journal of Cancer, individuals may want to talk to their health … Read more

Newly Diagnosed With Ovarian Cancer? Take a Breath, Then Follow These Steps

July 17, 2018 2:30 am
BY Jason Harris
The first thing a woman should do after receiving a diagnosis of ovarian cancer, according to Teresa P. Díaz-Montes, M.D., M.P.H., is nothing. At least not right away.

“You feel lost and confused, and everybody is going

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Triggering an Immune Response in Ovarian Cancer

July 17, 2018 2:04 am
by Mark L. Fuerst

A novel personalized vaccine made from an ovarian cancer patient’s tumor tissue and immune cells was found in early research to stimulate potent therapeutic immune responses, extending overall survival for patients with recurrent disease.

The vaccine,

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Study does not find causal association between assisted reproduction and ovarian cancer risk

July 12, 2018 7:04 pm

Following concerns over many years that hormonal stimulation of the ovaries necessary for IVF may increase the risk of ovarian cancer, a nationwide cohort study from Denmark has now concluded that any perceived increase in risk is actually a statistical … Read more

Engineering Plant Cells to Speed the Production of a Widely Used Cancer Drug

July 12, 2018 6:42 pm

Can a personalized cancer vaccine effectively treat ovarian cancer?

July 6, 2018 9:12 pm
In recent study published in Science Translational Medicine, researchers tested a personalized cancer vaccine for treating ovarian cancer.

For most advanced ovarian cancers, the current treatment is a combination of surgery and chemotherapy. Initially, patient response to this treatment

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The Future of Ovarian Cancer: PARP Inhibition ‘Leading the Way’

July 6, 2018 8:58 pm
By Brielle Urciuoli
PARP inhibitors have made for new and exciting treatment options for ovarian cancer, but there is still much more work to be done, according to Dennis J. Slamon, M.D., Ph.D.

Slamon, who is the director of both

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Infertility linked to increased risk for ovarian cancer

July 6, 2018 8:54 pm

Fertility drugs do not increase a woman’s risk of ovarian cancer, a new study suggests.

It did find that infertility itself is associated with an increased risk of ovarian cancer.

The researchers examined data from more than 58,000 women in … Read more

Genetic Screening Can Inform Women of Their Breast and Ovarian Cancer Risks

July 6, 2018 7:21 pm

One of the most unsettling aspects of cancer is the unknown.

There is the unknown of what is in store for you if you receive a diagnosis of cancer. But on a larger scale, we all

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Unraveling Role of Tumor Suppressor in Gene Expression and Ovarian Tumorigenesis

July 5, 2018 6:21 pm

The tumor suppressor protein ARID1A controls global transcription in ovarian epithelial cells, according to new research conducted at The Wistar Institute, which provided mechanistic insight into tumorigenesis mediated by ARID1A loss in ovarian cancer. Study results were published online in

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Endometriosis Not a Factor in Survival of Patients with Clear Cell Ovarian Cancer, Study Finds

July 5, 2018 6:11 pm

by Ana Pena

Endometriosis does not worsen or improve survival of patients with ovarian clear cell carcinoma, a study suggests.

Researchers found that for these patients, resistance to treatment with platinum-based chemotherapy is the most important predictor of poor outcome.… Read more

Can Anxiety and Early Life Adversity Affect Ovarian Cancer Outcomes?

June 27, 2018 6:21 pm

In women with a recent ovarian cancer diagnosis, decreased anxiety was found to be associated with better regulated cortisol profiles, according to a new study. Those with early life adversity and other factors associated with anxiety had sustained anxiety and … Read more

ASCO 2018: Dendritic Cell Vaccine

June 20, 2018 5:46 pm

Dendritic cell vaccine improved progression-free survival when administered sequentially after chemotherapy. The vaccine provides a promising maintenance treatment option to delay progression of epithelial ovarian carcinoma.

This outcome of an interim analysis of a phase II, open-label, randomized, multicenter trial … Read more

Bevacizumab Rechallenge Benefit in Recurrent Ovarian Cancer?

June 19, 2018 5:43 pm

A new study suggests that a rechallenge with bevacizumab in combination with platinum-based chemotherapy may prolong progression-free survival (PFS) in patients with recurrent ovarian cancer (ROC) who already received this agent during first-line treatment. The study was presented by Italian … Read more

My Stomach Pain Proved To Be Advanced Ovarian Cancer, and I Didn’t Like The Odds.

June 19, 2018 5:37 pm

By: Susan Lisovicz

I’m glad I was lying down when the doctor told me the true cause of my stomach pains.

“Well, you’ve got a tumor” were his first words to me. I had just awakened in a hospital bed … Read more

FDA Approves Bevacizumab Plus Chemotherapy in Advanced OC

June 14, 2018 7:32 pm

Today, the U.S. Food and Drug Administration (FDA) approved bevacizumab (Avastin) in combination with chemotherapy (carboplatin and paclitaxel) followed by bevacizumab as a single agent for the treatment of women with advanced (stage III or IV) ovarian cancer following initial … Read more