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Search Results for 'ovarian cancer screening'
Information and Support
May 2, 2018 6:58 pm
There are many places you can go online to learn more about cancer and obtain financial and psycho-social support. Here are a few examples:
21st Century C.A.R.E. (888-850-1622) – Provides financial assistance, education and support.
American Cancer Society (800-227-2345) – … Read more
Ovarian Cancer Basics
May 2, 2018 6:38 pm
Symptoms
Early detection of ovarian cancer is challenging because symptoms can be mild and vague and could apply to a variety of conditions, such as irritable bowel syndrome or ovarian cysts.
However, the most typical ovarian cancer symptoms, or changes … Read more
Genomics and Individualized Therapy
May 2, 2018 6:23 pm
Tumor biomarker testing can help inform treatment decisions for ovarian cancer patients. This information is discovered by testing the tumor for biomarkers, such as PD-L1, homologous recombination deficiency (HRD), tumor mutation burden (TMB), and microsatellite instability (MSI) and using next … Read more
AI partners with liquid biopsy for ‘robust’ identification of women with ovarian cancer
April 10, 2024 9:00 am
by Josh Friedman
Key takeaways:
AI-analyzed fragmentomes and protein biomarkers better distinguished women with ovarian cancer in screening.
Liquid biopsy assay outperformed CA125 analysis alone.
An artificial intelligence-driven algorithm used a novel liquid biopsy assay to differentiate women with ovarian … Read more
Women’s Cancers: Clinicians Research, Advise on Sexual Dysfunction
March 29, 2024 9:00 am
By Heidi Splete
Many women with cancer want advice for managing sexual function issues, and clinicians are tuning in, new studies suggest.
Decreased sexual function is a side effect of many types of cancer, notably uterine, cervical, ovarian, and breast … Read more
Cancer Prevention Strategies Linked to Mortality Reduction in BRCA Carriers
February 29, 2024 9:00 am
By Mike Basset
Risk management strategies including bilateral salpingo-oophorectomy (BSO) for ovarian cancer and MRI surveillance for breast cancer were associated with a significant reduction in mortality for women with BRCA1/2 sequence variations, according to results from two cohort studies … Read more
Diagnosing the “Silent Killer”: AI Tackles Early Stage Ovarian Cancer
January 26, 2024 9:00 am
By Fay Lin, PhD
A major bottleneck in early detection is the molecular heterogeneity between ovarian cancer (OC) patients, which limits the likelihood of identifying individual biomarkers that are shared among patients. In a new study “A personalized probabilistic … Read more
Claudine Isaacs, MD, on the Limitations of At-Home Genetic Tests for Hereditary Breast/Ovarian Cancers More than 95% of BRCA1 or BRCA1 pathogenic variants would have been missed by DTC testing, largest such study showed
November 8, 2023 9:00 am
By Mark Fuerst
Direct-to-consumer (DTC) genetic testing has limited use as a screening tool for identifying individuals at risk of hereditary breast or ovarian cancer, especially in those of non-Ashkenazi Jewish descent, researchers reported.
Most current DTC genetic tests evaluate … Read more
Study Finds Shortcomings in Monitoring Caregivers’ Emotional Health
October 27, 2023 4:58 pm
By Sharon Reynolds
Clearity offers psychosocial support to caregivers through our Steps Through OC program. If you would like personal one-to-one assistance with the stress and challenges associated with caring for a loved one with an ovarian cancer diagnosis, our … Read more
Dr Rebecca Brooks Covers Ovarian Cancer Risk Factors, Preventive Measures
September 29, 2023 9:00 am
By Hayden E. Klein
For Ovarian Cancer Awareness Month in September, Rebecca Brooks, MD, talked to The American Journal of Managed Care® (AJMC®) about how genetics and family history play a large role in ovarian cancer … Read more
New biomarker offers hope for earlier ovarian cancer detection
August 9, 2023 9:00 am
Ovarian cancer is particularly difficult to detect, as the disease often does not produce significant symptoms until it has reached late stages and caused metastasis. New screening methods would help physicians detect ovarian tumors early and dramatically increase the chances … Read more
Proteomics Pathway Diagnostic Helps Identify Platinum-Refractory Ovarian Cancers
August 9, 2023 9:00 am
A new study describes a new diagnostic approach that could help identify the 15% of women with ovarian cancer whose tumors are intrinsically refractory to standard platinum-based therapies, the most common type of chemotherapy for the disease.
Most ovarian cancers … Read more
DESTINY-PanTumor-02: Trastuzumab Deruxtecan Has Activity Against a Range of HER2-Expressing Solid Tumors
June 7, 2023 6:55 am
Key Points:
Interim results of the phase 2 trial DESTINY-PanTumor-02 show that T-DXd has broad activity across tumor types and a toxicity profile consistent with previous studies.
T-DXd had the lowest activity in pancreatic cancer, and this cohort was stopped … Read more
Exome sequencing identifies cancer predisposition-gene carriers screening guidelines miss
April 19, 2023 12:55 pm
by Jennifer Southall
Whole-exome sequencing identified carriers of predisposition genes for hereditary breast and ovarian cancer or Lynch syndrome who, under current guidelines, would not have qualified for genetic testing, according to study results.
The findings, presented at American Association … Read more
Tailored Phone Calls Increased Rate of Genetic Testing, Counseling for Hereditary Cancer Risk
March 2, 2023 9:44 am
by Alison Kanski
NEW YORK – Personalized phone discussions about genetic risk assessment increased the number of breast and ovarian cancer patients who got genetic testing or discussed their risk with a genetic counselor, a study from Rutgers Cancer Institute … Read more
OCRA Issues Consensus Statement Calling for Consideration of Fallopian Tube Removal to Prevent Ovarian Cancer
February 3, 2023 2:16 pm
by Jo Cavallo
The UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) has shown that general population screening did not significantly reduce ovarian and tubal cancer deaths, and the researchers concluded that such screening cannot be recommended. The findings from … Read more
Targeting FRα Enters a New Era in Ovarian Cancer and Beyond
January 16, 2023 9:41 am
by Anita T. Shaffer
Efforts to target the folate metabolism network have entered a new stage, with the approval of a novel therapy directed at folate receptor–α and the potential for additional agents aimed at that target in solid tumors.… Read more
Machine learning model builds on imaging methods to better detect ovarian lesions
November 29, 2022 11:37 am
by Beth Miller
(From left) The top row shows an ultrasound image of a malignant lesion, the blood oxygen saturation, and hemoglobin concentration. The bottom row is an ultrasound image of a benign lesion, the blood oxygen saturation, and hemoglobin … Read more
Mirvetuximab Soravtansine Generates Improvement in PROs Vs Chemotherapy in Advanced Ovarian Cancer
October 13, 2022 2:03 pm
by Chris Ryan
Treatment with mirvetuximab soravtansine elicited a statistically significant benefit vs investigator’s choice of chemotherapy for the OV28 abdominal/gastrointestinal symptom subscale in patients with folate receptor alpha–positive, advanced ovarian cancer.
Treatment with mirvetuximab soravtansine elicited a statistically significant … Read more
Identifying the Underlying Causes of Ovarian Cancer
October 6, 2022 1:48 pm
by Cedars-Sinai
New Studies Led by Cedars-Sinai Investigators Help Pinpoint Genetic Risk Factors Tied to Increased Risk of Ovarian Cancer and Suggest How to Better Identify Women Most At Risk
Image on left: Simon Gayther, PhD, professor of Biomedical Sciences, … Read more