The best way to prevent this deadly cancer is to remove multiple organs. And I’m about to do it.

June 24, 2024 9:00 am

Clearity’s Perspective: This article is written by a daughter whose mother was diagnosed with advanced ovarian cancer. She shares the story of her mother’s diagnosis and treatment and how her family handled learning of her mother’s inheritable genetic condition. Clearity

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Platinum-resistant ovarian cancer: mirvetuximab soravtansine benefits are maintained in patients who require dose modifications

June 20, 2024 9:00 am

As presented at the ESMO Gynaecological Cancers Congress 2024 (Florence, 20–22 June), a post-hoc analysis of the phase III MIRASOL (GOG 3045/ENGOT-ov55) trial in patients with high folate receptor alpha (FRalpha), platinum-resistant ovarian cancer revealed that even those who required Read more

One Patient Changed This Oncologist’s View of Hope. Here’s How.

June 12, 2024 9:00 am

By Sharon Worcester, MA

CHICAGO — Carlos, a 21-year-old, lay in a hospital bed, barely clinging to life. Following a stem cell transplant for leukemia, Carlos had developed a life-threatening case of graft-vs-host disease.

But Carlos’ mother had faith.

“I … Read more

Achieving High-Quality Care for Patients With Ovarian Cancer

June 10, 2024 9:00 am

Clearity’s Perspective: This article highlights that some people with ovarian cancer who live in certain geographic locations, like rural areas, may get treated at centers with less experience treating ovarian cancer and/or fewer resources to support whole-person needs. Clearity offers Read more

Dual Immunotherapy Improves Response Rates in Gynecologic Clear Cell Cancers

June 4, 2024 9:00 am

by Wayne Kuznar

CHICAGO — Clinical activity and survival outcomes improved with the addition of ipilimumab (Yervoy) to nivolumab (Opdivo) in patients with ovarian or other gynecologic clear cell carcinomas, according to results from the non-comparative phase II BrUOG 354 … Read more

No Benefit to Adding Atezolizumab to Chemo/Bevacizumab for Ovarian Cancer

June 2, 2024 9:00 am

by Silas Inman

The addition of atezolizumab (Tecentriq) to single-agent non–platinum-based chemotherapy and bevacizumab (Avastin) did not provide any additional benefits for patients with recurrent ovarian cancer, according to the final analysis of the phase 3 AGO-OVAR 2.29/ENGOT-ov34 study (NCT03353831) … Read more

Advanced Ovarian Cancer: Can Lymphadenectomy Be Avoided for Some Patients?

June 2, 2024 9:00 am

by The ASCO Post Staff

Some people with advanced epithelial ovarian cancer may safely avoid having their lymph nodes removed during surgery without it impacting their survival outcomes, helping to reduce the risk of postoperative complications. This research was presented … Read more

Estrogen-Only Hormone Therapy Linked to Increased Gynecologic Cancer Risk, But Estrogen-Progestin Combination Therapy Lowers It

June 1, 2024 9:00 am

by Aaron Tallent

Key Points:

  • Hormone replacement therapy (HRT) can reduce bothersome symptoms of menopause, but there is concern it may increase the incidence of certain cancers.
  • An analysis from the Women’s Health Initiative shows that estrogen-only HRT may increase
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Sydney researchers find differences in ovarian cancer risk factors by racial and ethnic groups

May 31, 2024 9:00 am

Researchers conducted an international study of more than 11,000 ovarian cancer cases found selected ovarian cancer risk factors vary for women of different racial and ethnic backgrounds.

Led by Dr Melissa Merritt and Dr Nicola Meagher from the Daffodil Centre … Read more

For some endometriosis-related ovarian cancers, timing is everything

May 28, 2024 9:00 am

by Van Andel Research Institute

Two types of endometriosis-related ovarian cancer arise from the same cells but likely at different stages of the menstrual cycle—a nuance that significantly influences treatment response, reports a recent study led by Van Andel Institute … Read more

Sister Study Cohorts Shows Association of Gential Talc Use and Ovarian Cancer

May 23, 2024 9:00 am

by Ariana Pelosci

Results of a recent study published in the Journal of Clinical Oncology highlighted the association of ovarian cancer with talcum powder (talc) use.1 The findings were from an extensive analysis of the Sister Study cohort.… Read more

Study reveals no survival benefit from systemic therapy in very advanced solid tumors

May 17, 2024 9:00 am

Clearity’s Perspective: Clearity knows that making decisions about continuing treatment when facing advanced ovarian cancer is complicated. Given the difficulty of these decisions, this article suggests having goals-of-care conversations with your medical providers when deciding whether or not to continue Read more

New Approach May Help People with Cancer Better Manage Depression, Pain, and Fatigue

May 14, 2024 9:00 am

Clearity offers emotional support to individuals with ovarian cancer through our Steps Through OC program. If you would like personal one-to-one assistance with the stress and challenges associated with an ovarian cancer diagnosis, our team of OC Counselors may be Read more

Yoga shows ‘most improvement’ in restoring brain health in long-term cancer survivors, Northeastern researcher says

May 10, 2024 9:00 am

by Cynthia McCormick Hibbert

For too many cancer survivors, life after treatment is fraught with a decline in cognitive function known as “chemo brain.”

newly published study by a Northeastern professor says that yoga might hold the key to … Read more

LGBTQ+ Voices: Listening to Sexual and Gender Minority People Affected by Cancer

May 1, 2024 9:00 am

by Edward Winstead

This story has an accompanying Q&A with Dr. Gwendolyn Quinn, Ph.D., of the New York University Perlmutter Cancer Center, on some of the challenges faced by LGBTQ+ people with cancer and ways to address them.

After surgery … Read more

New FDA Guidance Looks to Improve Clinical Trial Enrollment and Diversity

April 30, 2024 9:00 am

by Sabrina Serani

The FDA announced new guidance to expand eligibility criteria with the goal of improving participation and diversity in oncology clinical trials.These 3 areas of change include laboratory values, washout periods, and performance status.

While the FDA notes … Read more

AI partners with liquid biopsy for ‘robust’ identification of women with ovarian cancer

April 10, 2024 9:00 am

by Josh Friedman

Key takeaways:

  • AI-analyzed fragmentomes and protein biomarkers better distinguished women with ovarian cancer in screening.
  • Liquid biopsy assay outperformed CA125 analysis alone.

An artificial intelligence-driven algorithm used a novel liquid biopsy assay to differentiate women with ovarian … Read more

Enhertu Gets Tumor-Agnostic FDA Approval for HER2-Positive Cancers

— About half of patients responded, duration of response as long as 19 months in three trials

April 5, 2024 9:00 am

By Charles Bankhead

The FDA granted tumor-agnostic accelerated approval to trastuzumab deruxtecan (Enhertu) for previously treated unresectable or metastatic HER2-positive (immunohistochemistry [IHC] 3+) solid cancers.

The action represents the first tumor-agnostic approval for an antibody-drug conjugate targeting HER2-positive tumors. According … Read more

Stress-Induced Immune Changes May Help Cancer Spread

April 2, 2024 9:00 am

Clearity’s Perspective: This article highlights the importance of learning ways to cope with and manage stress after an ovarian cancer diagnosis. The study, performed only on mice, suggests that there may be a link between overproduction of stress hormones and Read more