A Rising Trend in Cancer Care Targets Physical, Existential Threats Patients Confront

May 6, 2019 6:00 pm

By Sarah Elizabeth Richards

Photo: Diagnosed with terminal metastatic breast cancer, Tori Geib started seeing a palliative care coach in Columbus, Ohio. She says the treatment helped improve the quality of her life. (Matt Vojacek)

When Tori Geib learned she … Read more

Epithelial Ovarian Cancer: BRCA Mutations, Brain Mets, and Breastfeeding

May 6, 2019 5:00 pm

By Kristin Jenkins

The presence of a BRCA germ line mutation in patients with invasive epithelial ovarian cancer may confer a short-term survival advantage, but is not associated with a reduction in long-term mortality, researchers found.

A follow-up study comparing … Read more

Liquid Biopsies Can Point to Best Ovarian Cancer Treatment

May 6, 2019 4:00 pm

DNA shed by tumors into the bloodstream is starting to be used for the early detection of cancer and for monitoring how well treatment is working. Such DNA, which is called circulating tumor DNA (ctDNA), hasn’t been quite as helpful

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Study Shows Ovarian Cancer Survival Increase

May 3, 2019 5:00 pm

A gynecologic oncologist at the Stephenson Cancer Center at OU Medicine was a national leader of a newly published research study that reveals good news for women with ovarian cancer—longer survival times plus a treatment option that causes fewer difficult … Read more

Scientists Identify Genes Tied to Increased Risk of Ovarian Cancer

May 1, 2019 6:00 pm

A team of researchers at UCLA’s Jonsson Comprehensive Cancer, Cedars-Sinai Cancer and Dana-Farber Cancer Institute have newly identified 34 genes that are associated with an increased risk for developing the earliest stages of ovarian cancer. The findings, published today in … Read more

Managing Chemotherapy Side Effects for Ovarian Cancer

May 1, 2019 5:15 pm

By Dr. Leslie Boyd

Ovarian cancer produces the type of tumor that oncologists like to call “chemo-sensitive”—which is pretty good news for anyone diagnosed. Ovarian cancer cells have been shown to respond well to a combination of chemo drugs, which … Read more

Changes in the Metabolism of Normal Cells Promotes the Metastasis of Ovarian Cancer Cells

May 1, 2019 5:00 pm

A systematic examination of the tumor and the tissue surrounding it—particularly normal cells in that tissue, called fibroblasts—has revealed a new treatment target that could potentially prevent the rapid dissemination and poor prognosis associated with high-grade serous carcinoma (HGSC), a … Read more

6 Questions to Ask Your Doctor After an Ovarian Cancer Diagnosis

April 30, 2019 5:00 pm

Two of the key points this article touches on refer to finding a clinical trial and seeking mental health support. At Clearity, we can help! Check out our Clinical Trial Finder, as well as Steps Through OC, a Read more

Impact of Somatic Molecular Profiling on Clinical Trial Outcomes in Rare Epithelial Gynecologic Cancer Patients

April 25, 2019 6:00 pm

Given that the limited number of patients and differences in biologic behavior pose challenges in conducting clinical trials in rare malignancies, researchers determined whether using genomic profiling for rare gynecologic malignancies is feasible and have clinical utility. They analyzed somatic

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Still No Benefit of IP Chemo for Ovarian Cancer

April 24, 2019 5:00 pm

By Charles Bankhead

No PFS or OS benefit, more toxicity with IP verses IV regimens

Final results of a highly anticipated randomized trial failed to show a survival benefit with intraperitoneal (IP) chemotherapy in patients with newly diagnosed advanced ovarian … Read more

Imaging System Helps Surgeons Remove Tiny Ovarian Tumors

April 23, 2019 5:00 pm

By Anne Trafton

More effective surgery could boost survival rates for ovarian cancer.

Ovarian cancer is usually diagnosed only after it has reached an advanced stage, with many tumors spread throughout the abdomen. Most patients undergo surgery to remove as

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Smart Nanoparticles Help Improve Treatment of Peritoneal Tumors

April 22, 2019 5:00 pm

Research carried out at the University of Tartu Faculty of Medicine used nanoparticles for the development of new imaging and treatment methods for peritoneal cancers. Tests showed that precision-guided anticancer nanoparticles have improved efficacy and reduced side effects.

One of … Read more

Social Media Posts Identify Needs, Concerns of Patients with Ovarian Cancer

April 18, 2019 5:00 pm

By Beth Fand Incollingo and Kristie L. Kahl

Patients with ovarian cancer tend to underreport their most challenging symptoms; however, an analysis of their online comments could give health care providers insight into how to help.

A machine learning approach … Read more

Niraparib Offers New Option in Heavily Pretreated Ovarian Cancer

April 17, 2019 7:00 pm

By Dave Levitan

Niraparib showed promising and clinically relevant activity as therapy for heavily pretreated patients with ovarian cancer, according to a new phase II study. This was particularly true among women with homologous recombination deficiency (HRD)-positive tumors.

“Although most … Read more

Types of Drugs Used to Treat Cancer

April 15, 2019 7:00 pm

By Andrea S. Blevins Primeau, PhD, MBA

There are many different types of agents used in the treatment of cancer, and they can generally be classified according to molecule type or their basic mechanism of action. Different cancer types have … Read more

Ovarian Cancer Patients Undertested for Mutations that Could Guide Clinical Care

April 9, 2019 4:00 pm

By Krista Conger

A large study of women with breast and ovarian cancer has revealed significant gaps between national guidelines for genetic testing and actual testing practices, according to researchers from Stanford and five other institutions.

Fewer than a quarter … Read more

23andMe DTC Breast and Ovarian Cancer Risk Test Misses Almost 90 Percent of BRCA Mutation Carriers

April 5, 2019 5:00 pm

By Julia Karow

A study led by researchers at Invitae has found that 23andMe’s direct-to-consumer BRCA test, which tests for three common variants in the BRCA1 and BRCA2 genes and is authorized by the US Food and Drug Administration, misses … Read more

Study: Birth Control Pills Protect Against Aggressive Ovarian Cancer

April 3, 2019 5:00 pm

“The longer the history of oral contraceptive use, the greater the protection we observed in terms of reduced chance of dying from aggressive ovarian cancer,” said study first author Jennifer Mongiovi.

The protection that birth control pills offer against ovarian … Read more

Ovarian Cancer’s New Identity: A Chronic Disease

April 1, 2019 4:45 pm

By Deborah Abrams Kaplan

Women with this disease are living longer, despite common recurrence.

When Luci Berardi received a stage 4 ovarian cancer diagnosis in October 2010, she did not want to know her chances of survival. The physician told … Read more

Initial Phase 2 Data From an IMV Clinical Study Continues to Demonstrate DPX-Survivac’s Prior Trend as a Potential Monotherapy Treatment for Advanced Ovarian Cancer

March 26, 2019 5:00 pm

IMV Inc., a clinical stage immuno-oncology corporation, today announced preliminary data from the phase 2 cohort of the DECIDE clinical study. Six patients receiving DPX-Survivac monotherapy with intermittent low-dose cyclophosphamide (mCPA) have reached the first CT scan assessment with key … Read more