Benefit of Single-Agent Carboplatin in Vulnerable, Elderly Patients With Ovarian Cancer

June 5, 2019 7:00 pm

By Leah Lawrence

Single-agent carboplatin conferred significantly worse survival outcomes in vulnerable, elderly patients with stage III/IV epithelial ovarian cancer compared with weekly or every 3 weeks carboplatin/paclitaxel, according to results of the EWOC-1 trial (abstract 5508), which … Read more

Scientists Uncover Mechanism of Action for Promising Cancer Compound

June 5, 2019 5:00 pm

University of North Carolina Lineberger Comprehensive Cancer Center researchers have uncovered the mechanism that explains how an investigational cancer therapeutic might be working—a finding that they believe could be important for the design of potential new therapies.

In the journal … Read more

Chemo-Free Combo Boosts PFS in Recurrent Ovarian Cancer

June 4, 2019 6:00 pm

By Ian Ingram

Benefit seen across all subgroups for patients with platinum-sensitive disease.

Ovarian cancer patients with recurrent, platinum-sensitive disease experienced a longer interval without disease progression when bevacizumab (Avastin) was added to niraparib (Zejula), a phase II study found.… Read more

Medicaid Expansion Narrows Racial Gaps in Access to Timely Ovarian Cancer Care

June 4, 2019 5:00 pm

by Paige Minemyer

Medicaid expansion may have significantly reduced racial disparities in access to earlier ovarian cancer treatment, according to a new study.

The findings, which were presented at the American Society of Clinical Oncology’s annual meeting, show that … Read more

ACA May Impact Ovarian Cancer Outcomes

June 2, 2019 5:00 pm

By John Schieszer

Under the Affordable Care Act (ACA), women with ovarian cancer were more likely to be diagnosed at an early stage and receive treatment within 30 days of diagnosis, according to researchers at Johns Hopkins School of Medicine, … Read more

How to Talk to Your Kids About Your Cancer Diagnosis

June 1, 2019 5:00 am

By 

Helpful advice from experts and a mom who’s been there twice.

When you’re diagnosed with cancer, processing it is hard, and figuring out how to tell your kids about it just adds to the stress and … Read more

Choosing Sides: Treatment Decisions for Recurrent Ovarian Cancer Must Consider Side Effects

May 30, 2019 6:00 pm

Patients with ovarian cancer who experience disease recurrences can have potentially helpful options from a large array of drugs, each of which can bring on side effects.

Luckily, doctors have a variety of ways to relieve or prevent these discomforts.

Read more

A Letter to My Newly Diagnosed Self

May 24, 2019 1:00 pm

By Kelly Irvin

A second ovarian cancer recurrence in three years prompted this review of lessons learned. If I could go back three and a half years and give advice to my newly diagnosed self, what would I say?

This … Read more

‘This terrible disease’: Ovarian cancer is deadly, but new tests, treatments start to emerge

May 18, 2019 5:00 pm

By Sarah Elizabeth Richards

Photo: Liz Laats with husband Andy Laats and their three children. She died three years ago of ovarian cancer. The San Diego resident had suffered through 88 rounds of chemotherapy during 10 treatment regimens over six Read more

CRISPR Reveals New Cancer Drug Targets through ID of Critical Gene Fusion Regions

May 16, 2019 6:00 pm

In what they claim is the first large-scale systematic analysis of thousands of gene fusions in human cancers, scientists have identified a gene fusion that could represent a novel drug target for multiple cancers. Through their studies, the largely U.K.-based … Read more

Study Identifies How Cancer Drug Inhibits DNA Repair in Cancer Cells

May 15, 2019 6:00 pm

According to researchers at Yale Cancer Center, a cancer drug thought to be of limited use possesses a superpower of sorts: It is able to stop certain cancer cells from repairing their DNA in order to survive. The study, published … Read more

System-Based Intervention Cuts Racial Disparities in Cancer Care

May 14, 2019 6:00 pm

By Jessica Kent

A system-based intervention reduced racial disparities among black and white cancer patients.

A pragmatic, system-based intervention decreased racial disparities in cancer treatment and outcomes for black patients with early-stage breast cancer.

In a five-year study conducted at … Read more

Research Could Lead to More Precise Diagnosis and Treatment of Ovarian Cancer

May 8, 2019 5:00 pm

By Michael Brown

Oncologists may soon have an accurate and inexpensive way of differentiating between types of ovarian cancer that will improve how patients are treated, thanks to findings from a national research study co-led out of the University of … Read more

A Rising Trend in Cancer Care Targets Physical, Existential Threats Patients Confront

May 6, 2019 6:00 pm

By Sarah Elizabeth Richards

Photo: Diagnosed with terminal metastatic breast cancer, Tori Geib started seeing a palliative care coach in Columbus, Ohio. She says the treatment helped improve the quality of her life. (Matt Vojacek)

When Tori Geib learned she … Read more

Epithelial Ovarian Cancer: BRCA Mutations, Brain Mets, and Breastfeeding

May 6, 2019 5:00 pm

By Kristin Jenkins

The presence of a BRCA germ line mutation in patients with invasive epithelial ovarian cancer may confer a short-term survival advantage, but is not associated with a reduction in long-term mortality, researchers found.

A follow-up study comparing … Read more

Liquid Biopsies Can Point to Best Ovarian Cancer Treatment

May 6, 2019 4:00 pm

DNA shed by tumors into the bloodstream is starting to be used for the early detection of cancer and for monitoring how well treatment is working. Such DNA, which is called circulating tumor DNA (ctDNA), hasn’t been quite as helpful

Read more

Study Shows Ovarian Cancer Survival Increase

May 3, 2019 5:00 pm

A gynecologic oncologist at the Stephenson Cancer Center at OU Medicine was a national leader of a newly published research study that reveals good news for women with ovarian cancer—longer survival times plus a treatment option that causes fewer difficult … Read more

Scientists Identify Genes Tied to Increased Risk of Ovarian Cancer

May 1, 2019 6:00 pm

A team of researchers at UCLA’s Jonsson Comprehensive Cancer, Cedars-Sinai Cancer and Dana-Farber Cancer Institute have newly identified 34 genes that are associated with an increased risk for developing the earliest stages of ovarian cancer. The findings, published today in … Read more

Managing Chemotherapy Side Effects for Ovarian Cancer

May 1, 2019 5:15 pm

By Dr. Leslie Boyd

Ovarian cancer produces the type of tumor that oncologists like to call “chemo-sensitive”—which is pretty good news for anyone diagnosed. Ovarian cancer cells have been shown to respond well to a combination of chemo drugs, which … Read more

Changes in the Metabolism of Normal Cells Promotes the Metastasis of Ovarian Cancer Cells

May 1, 2019 5:00 pm

A systematic examination of the tumor and the tissue surrounding it—particularly normal cells in that tissue, called fibroblasts—has revealed a new treatment target that could potentially prevent the rapid dissemination and poor prognosis associated with high-grade serous carcinoma (HGSC), a … Read more