Triggering an Immune Response in Ovarian Cancer

July 17, 2018 2:04 am
by Mark L. Fuerst

A novel personalized vaccine made from an ovarian cancer patient’s tumor tissue and immune cells was found in early research to stimulate potent therapeutic immune responses, extending overall survival for patients with recurrent disease.

The vaccine,

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Infertility linked to increased risk for ovarian cancer

July 6, 2018 8:54 pm

Fertility drugs do not increase a woman’s risk of ovarian cancer, a new study suggests.

It did find that infertility itself is associated with an increased risk of ovarian cancer.

The researchers examined data from more than 58,000 women in … Read more

Unraveling Role of Tumor Suppressor in Gene Expression and Ovarian Tumorigenesis

July 5, 2018 6:21 pm

The tumor suppressor protein ARID1A controls global transcription in ovarian epithelial cells, according to new research conducted at The Wistar Institute, which provided mechanistic insight into tumorigenesis mediated by ARID1A loss in ovarian cancer. Study results were published online in

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Endometriosis Not a Factor in Survival of Patients with Clear Cell Ovarian Cancer, Study Finds

July 5, 2018 6:11 pm

by Ana Pena

Endometriosis does not worsen or improve survival of patients with ovarian clear cell carcinoma, a study suggests.

Researchers found that for these patients, resistance to treatment with platinum-based chemotherapy is the most important predictor of poor outcome.… Read more

Can Anxiety and Early Life Adversity Affect Ovarian Cancer Outcomes?

June 27, 2018 6:21 pm

In women with a recent ovarian cancer diagnosis, decreased anxiety was found to be associated with better regulated cortisol profiles, according to a new study. Those with early life adversity and other factors associated with anxiety had sustained anxiety and … Read more

Is Adjuvant Chemo Warranted In Stage I Ovarian Clear Cell Carcinoma?

May 31, 2018 7:11 pm

In patients with stage I ovarian clear cell carcinoma, the use of adjuvant chemotherapy was associated with superior overall survival (OS), according to results of a large, retrospective cohort study.

The finding, published in Gynecologic Oncology, provides further evidence … Read more

Fully Reprogrammed Virus Offers New Hope As Cancer Treatment

May 25, 2018 7:04 pm

A cancer treatment that can completely destroy cancer cells without affecting healthy cells could soon be a possibility, thanks to research led by Cardiff University.

The team of researchers has successfully ‘trained’ a respiratory virus to recognise ovarian cancer and … Read more

Scientists Identify Why Some May Be Resistant To PARP Inhibitor Drugs

May 21, 2018 6:33 pm

A team of scientists from the Institute of Cancer Research in London has identified DNA mutations which makes cancer cells resistant to a new class of drugs called PARP inhibitors, used for the treatment of breast and ovarian cancers.

The … Read more

Why Ovarian Cancer Spreads and How We Might Stop It

May 9, 2018 6:44 pm

New research has revealed exactly why ovarian cancer spreads to the peritoneal cavity. Existing drugs could be repurposed to stop this from happening.

In the United States, ovarian cancer is estimated to affect around 20,000 women every year.

In 2014, … Read more

PapSEEK: Potential Screening Test for Gynecologic Cancers

March 23, 2018 7:29 pm

A sample obtained from routine Papanicolaou (Pap) tests used for cervical cancer screening can be subjected to a multiplex panel test, dubbed PapSEEK, to determine whether the sample is positive for endometrial or ovarian cancer, two gynecologic cancers for which … Read more

Liquid Biopsy Tests in People with Cancer: An Expert Review

March 14, 2018 7:03 pm

Use of tests that assess genomic variants in circulating tumor DNA (ctDNA) is on the rise. A new joint review from the American Society of Clinical Oncology (ASCO) and the College of American Pathologists (CAP) provides an assessment of evidence … Read more

Hidden Burdens: The Effects of an Ovarian Cancer Diagnosis

February 23, 2018 6:51 pm

By: Kristie Kahl

After a cancer diagnosis and treatment, one may question when they will actually start to feel “normal” again, whatever that may be. The Ovarian Cancer Prognosis and Lifestyle (OPAL) study set out to help women with ovarian … Read more

Blood Test To Detect 8 Cancers Early Gives Promising Results

January 22, 2018 11:06 pm

Scientists are reporting progress on a blood test to detect many types of cancer at an early stage, including some of the most deadly ones that lack screening tools now.

Many groups are working on liquid biopsy tests, which look … Read more

BRCA1 Methylation Tied to Ovarian Cancer Risk

January 18, 2018 4:26 am

BRCA1 mutations are well-known to predispose to ovarian cancer risk. But now a new study, appearing in the Annals of Internal Medicine, suggests that methylation of normal BRCA1 genes might be a major ovarian cancer risk factor. In this Read more

Heated Abdominal Chemo Bath Improves Ovarian Cancer Survival

January 17, 2018 5:00 pm

By Gene Emery

A heated chemotherapy organ bath circulated throughout the abdomen after surgery can significantly prolong a woman’s survival with advanced ovarian cancer, according to doctors testing the new treatment.

Patients who underwent the experimental procedure at 8 hospitals … Read more

Fallopian Tube Removal May Help Prevent Most Common Ovarian Cancer

December 20, 2017 7:52 pm

A study published in October showed that high-grade serous ovarian carcinomas (HGSOC), which account for about 75 percent of ovarian cancers, originate with abnormal cells in the fallopian tubes an average of seven years before the disease develops. This understanding … Read more

Heart Drug Linked to Extra Years for Cancer Patients

October 20, 2015 11:00 am

A common heart drug called a beta blocker was associated with a striking increase in survival for women with ovarian cancer in a study that suggests a possible new strategy for treating a variety of tumors.

Researchers analyzing a database … Read more