By Clayton Boldt, Ph.D
Advanced ovarian cancer most commonly metastasizes to the omentum, a layer of fatty tissue that wraps around and protects internal organs in the abdomen, but the reasons for this have not been well-understood. In a new … Read more
A drug known as SP-2577 could help enable the body’s own immune system to attack ovarian cancer, according to a study led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.
Published today in the scientific … Read more
According to new research published in Clinical and Translational Immunology, a new cancer vaccine is ready for human trials following its success in preclinical studies.
By Alana Hippensteele
The vaccine was recently developed by a research team based at The … Read more
High-grade serous epithelial ovarian cancer may be detected earlier in the course of the disease by testing for TP53 clonal variants in DNA from Pap tests.
By Leah Lawrence
High-grade serous epithelial ovarian cancer may be detected earlier in the … Read more
High-grade serous ovarian cancer (HGSOC) is characterized by a high level of intrinsic heterogeneity in the tumor-immune microenvironment that is modified by chemotherapy, according to findings published in Nature Genetics.
HGSOC, a common and … Read more
A study presented at the AACR Virtual Annual Meeting II showed a significant decrease in mortality rate for patients with epithelial ovarian cancer when treated with lipophilic statins, supporting the further evaluation of statins to treat ovarian cancer in randomized … Read more
Inhibiting the JAK/STAT pathway could represent a potential treatment for high-grade serous ovarian cancer, according to a single-cell analysis.
Researchers led by the Broad Institute’s Aviv Regev used single-cell RNA sequencing (scRNA-seq) to analyze about 11,000 cells from ascites from … Read more
University of British Columbia (UBC) researchers have led an international team in developing a new test to better diagnose different types of ovarian cancer, a tool that could one day guide and improve treatment options for women diagnosed with the … Read more
By Neil Osterweil
FROM SGO 2020
Patients with gynecologic malignancies who consumed only water for 24 hours before and 24 hours after each chemotherapy cycle had fewer dose delays and reductions compared with patients who didn’t fast, results of a
By Jennifer Smith
A survey of gynecologic cancer survivors has revealed why some of these patients don’t participate in clinical trials.
By Susan Moench, PhD, PA-C
Results of a randomized clinical trial evaluating video-assisted genetic counseling followed by either formal genetic counseling or direct referral for genetic testing in women with ovarian/fallopian/peritoneal cancer receiving adjuvant therapy showed that a significantly higher … Read more
BOSTON – In patients with advanced ovarian cancer, a combination of drugs known as immune checkpoint inhibitors and PARP inhibitors can produce powerful remissions, clinical trials have shown, but up until now investigators haven’t been able to predict which patients … Read more
By Will Boggs MD
NEW YORK (Reuters Health) – Pathogenic variants in RAD51C and RAD51D are associated with an increased risk of ovarian and breast cancer, researchers report.
“RAD51C and RAD51D are included in cancer gene panels that are widely … Read more
CLEVELAND, Ohio (March 4, 2020)–Women who proactively have their ovaries removed to minimize their cancer risk may face a greater risk–premature death because of heart disease. That’s according to a new study that identifies an increased risk for women with … Read more
By Cancer Research UK
A genetic study has found evidence to suggest that women who take statins in the long term could be less likely to develop ovarian cancer, according to new research funded by Cancer Research UK published today … Read more
Researchers have developed a simple blood test that measures the body’s own immune response to improve diagnosis of ovarian cancer.
Ovarian cancer is one of the most common gynecologic cancers, with the highest mortality rate. About 300,000 new cases are … Read more
By Christina Bennett, MS
Regardless of birthplace, women who are Asian Pacific Islanders may have a higher risk of developing ovarian clear cell cancer compared with other ethnicities, according to a population-based retrospective cohort study. The findings were recently published … Read more
By Kashmira Gander
Taking a single dose of a psychedelic compound found in magic mushrooms can ease symptoms of anxiety and depression in cancer patients for years, according to a study.
Almost five years after taking the compound psilocybin while … Read more
By Ian Ingram
— With some 250,000 participants, study rules out all but smallest risk increases
New research on a quarter-million women from four U.S. cohorts found no significant association between ovarian cancer and the use of powder-based products in … Read more
By Marissa Wexler, MS
Endometriosis does not seem to significantly affect ovarian cancer prognosis and survival in patients of reproductive age, a small study suggests.
However, more research is needed to identify factors associated with the progression of endometriosis to … Read more
