Ovarian Cancer Screening Isn’t as Simple as Getting an Ultrasound

October 26, 2018 7:26 pm

By Korin Miller

In fact, there’s no reliable screening test, period.

Ovarian cancer is one of those diseases you probably assume you’re being screened for when you go to your well-woman exams, but that’s not really the case. Ovarian cancer … Read more

Real-World Experience Differs from Trial Results for Niraparib in Recurrent Ovarian Cancer

October 25, 2018 1:11 am

By 

Real-world experience of adverse events with the oral PARP inhibitor niraparib in patients with platinum-sensitive recurrent ovarian cancer at a 200 mg daily dose differed from those most commonly seen in the phase 3 clinical trial at … Read more

Ovarian Cancer ‘Breakthrough’ Drug Prevents Disease Returning for Years

October 22, 2018 4:35 pm

By 

A new ovarian cancer treatment dramatically reduces the chances of the disease returning, a study has shown.

Doctors have hailed the results of a “breakthrough” trial which they say opens the possibility that many more women suffering … Read more

Diagnosis of ovarian cancer delayed by woeful lack of awareness

October 18, 2018 4:24 pm

Most comprehensive survey of women with ovarian cancer ever undertaken suggests raising awareness of the disease could improve outcomes for women.

A global study of women with ovarian cancer has found that two thirds of women had never heard of … Read more

New Blood Test Could Spare Cancer Patients From Unnecessary Chemotherapy

October 17, 2018 10:02 pm

Cancer patients could be spared unnecessary chemotherapy – and its side effects – by a new blood test that is in clinical trials at more than 40 hospitals in Australia and New Zealand.

The trials, led by Melbourne researchers, are … Read more

Ovarian Cancer Thwarts Immune Cells by Revving up Stress

October 12, 2018 11:30 pm

Ovarian tumors disable the immune system’s killer T cells—which protect the body by destroying infected or malignant cells—enabling the disease to flourish unchecked, according to a new study by Weill Cornell Medicine scientists. The findings show that adverse conditions within … Read more

Crosstalk Between Fallopian Tube, Ovary May Drive the Spread of Ovarian Cancer

October 9, 2018 5:31 pm

New research from the University of Illinois at Chicago shows that cancer cells in the fallopian tube affect normal chemical signaling between reproductive tissues and stimulate the release of norepinephrine, a small molecule hormone, from the ovary.

Reported in ACS Read more

Early Clinical Trials Showing Promise for New Kind of Cancer Vaccine

September 30, 2018 3:14 pm

By Rich Haridy

Promising early results are in from a phase 1 clinical trial into the safety and efficacy of a new cancer vaccine. The new treatment is designed to stimulate the immune system into attacking certain cancers known to … Read more

BRCA1 Methylation Level May Predict Which Ovarian Cancer Patients Respond to PARP Inhibitors

September 28, 2018 8:37 pm

The extent to which the BRCA1 promoter is methylated could signal an ovarian tumor’s susceptibility to PARP inhibitor treatment, a new study has found.

PARP inhibitor treatment has been effective in treating some patients with high-grade serous ovarian carcinoma with … Read more

Novel Biomarker Found in Ovarian Cancer Patients Can Predict Response to Therapy

September 27, 2018 6:58 pm

Despite months of aggressive treatment involving surgery and chemotherapy, about 85 percent of women with high-grade wide-spread ovarian cancer will have a recurrence of their disease. This leads to further treatment, but never to a cure. About 15 percent of

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Contraceptive Pill Linked with Reduced Risk of Ovarian Cancer

September 27, 2018 5:31 pm

By 

Researchers not sure apparent protective effect extends to progestin only products such as mini pill and implants.

Women who use modern forms of the combined pill are at a lower risk of developing ovarian cancer than women … Read more

To Test or Not To Test: A Thorny Question in Ovarian Cancer Maintenance

September 19, 2018 9:28 pm

BY Kelly Irvin

I’ve officially entered the twilight zone. No, not the one Rod Serling spoke of on that classic TV show. This is that murky, dark period when the tumor markers associated with ovarian cancer start creeping up. While … Read more

CTLA4 Targeted Therapy Plus PD-1 Targeted Therapy Could Benefit Women With Ovarian Cancer

September 19, 2018 12:22 am

An analysis of the NRG Oncology clinical trial NRG-GY003 suggests that adding ipilimumab, a monoclonal antibody that targets the protein receptor CTLA-4, to a regimen with the checkpoint inhibitor nivolumab could improve the proportion with tumor response and progression-free survival … Read more

Blocking ovarian cancer’s energy supply helps curb spread

September 18, 2018 6:45 pm
It is often the case that an ovarian cancer diagnosis reveals that the tumor has already spread to nearby tissue. Now, scientists have discovered a potential way to cut off the energy supply fueling this invasive
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Squelching Ovarian Cancer: The Not-So-Silent Killer

September 17, 2018 12:08 am

By Diane Mapes

Despite its long-standing nickname, ovarian cancer isn’t really a silent killer. There are symptoms; it’s just that they whisper or are commonly mistaken for something else, like aging or irritable bowel syndrome. As a result of this

Read more

New Developments in Ovarian Cancer Treatment Are Showing Promise

September 14, 2018 4:29 pm

Cancer is never an easy foe, but some types are more stubborn than others. Ovarian cancer is one of the hardest to treat.

But there are signs of progress. Several recent studies have used new combination treatment strategies, including a … Read more

Study Cracks Open the Secrets of the Cancer-Causing BRCA1 Gene

September 12, 2018 12:21 am

By Sharon Begley

Lawsuits didn’t do it, public shaming didn’t do it, patients and doctors banding together to “free the data” couldn’t do it: For 22 years Myriad Genetics, one of the oldest genetic testing companies, has refused to make … Read more

Drug combination gives ‘exciting’ results in ovarian and lung cancer in early trial

August 24, 2018 1:58 am

Combining a new targeted cancer drug with chemotherapy has shown promise in an early clinical trial, in patients with ovarian or lung cancer for whom all other treatments had failed.

The combination of targeted drug vistusertib along with paclitaxel chemotherapy … Read more

Scientists identify mutational signatures in ovarian cancer

August 22, 2018 4:52 pm

Researchers at Cancer Research UK, Imperial College London and the University of Cambridge have identified distinct patterns of genetic mutation among patients with ovarian cancer that could help them understand the disease and personalise treatment … Read more