By: Hillary Theakston, Executive Director of The Clearity Foundation
In May, for the first time, the U.S. Food and Drug Administration approved a cancer drug for patients whose tumors are defined by a specific genetic feature (biomarker), rather than by … Read more
The introduction of PARP inhibitors revolutionized the treatment of ovarian cancer, providing much-needed therapeutic options. However, clinical challenges remain as many patients are not candidates for PARP inhibitors and responses are often short-lived. Furthermore, biomarkers have not been established to … Read more
Immunotherapy treatments for cancer are having a moment.
A recent survey of patients with ovarian cancer has found that many of them are uncertain of what to expect after diagnosis, and this uncertainty can be challenging. More than half of the patients (53 percent) surveyed indicated that the … Read more
Colon, pancreatic, stomach, or ovarian cancer; it increasingly shouldn’t matter. In an era of precision medicine, the treatment approach should reflect the genetic makeup of the person’s tumor and the presence or absence of key biomarkers.
That ethos was set … Read more
Most women diagnosed with ovarian cancer undergo surgery to remove as many of the tumors as possible. However, it is usually impossible to eliminate all of the cancer cells because they have spread throughout the abdomen. Surgery is therefore followed … Read more
Most women diagnosed with ovarian cancer undergo surgery to remove as many of the tumors as possible. However, it is usually impossible to eliminate all of the cancer cells because they have spread throughout the abdomen. Surgery is therefore followed … Read more
By: Marcella Lee, CBS 8 Anchor/Reporter
A local non-profit is working to improve ovarian cancer survival rates by guiding patients into a new frontier.
Ovarian cancer is known as a silent killer because symptoms are vague like: bloating, abdominal or … Read more
Latest results from a mid-stage trial of ImmunoGen Inc’s experimental antibody-drug conjugate show that it shrinks or stabilizes tumors in nearly half of advanced ovarian cancer patients with at least medium levels of a key biomarker whose disease has become … Read more
One in four women with ovarian cancer develop blood clots, and over 10% develop clots during neoadjuvant chemotherapy given before surgery, according to a study published online May 5 in Obstetrics & Gynecology.
Past efforts at preventing blood clots in … Read more
In the treatment of advanced ovarian cancer, PARP inhibitors, including olaparib (Lynparza), rucaparib (Rubraca), and niraparib (Zejula), are stealing the limelight, explains Dennis Scribner, MD.
In an interview with Targeted Oncology, Scribner, a gynecologic oncologist at Arizona Oncology, discussed … Read more
Targeting the immune system to fight cancer is not new: in 1891, New York bone sarcoma surgeon William B. Coley injected a patient with an inoperable malignant tumor with streptococcal organisms. His theory was that the resulting severe bacterial infection, … Read more
Johnson & Johnson was ordered by a St. Louis jury to pay more than $110 million to a Virginia woman who blamed her ovarian cancer on the company’s talcum products.
Imerys Talc America, which provided the talc to J&J, was … Read more
Adding bevacizumab to platinum-based chemotherapy may improve survival among women with recurrent ovarian cancer, according to a study published in Lancet Oncology.1
Bevacizumab is emerging as an effective strategy as a first-line or maintenance therapy for recurrent ovarian … Read more
Researchers have been trying to understand why up to 85 percent of women experience recurrence of high-grade serous ovarian cancer — the most common subtype of ovarian cancer — after standard treatment with the chemotherapy drug carboplatin.
Preclinical research from … Read more
Teri Woodhull is decidedly proactive. A strong family history of breast cancer led her to undergo a preventive bilateral mastectomy at age 30. Seventeen years later, she was diagnosed with stage 3b high-grade serous epithelial ovarian cancer.
“I do have … Read more
Myriad Genetics had been exclusively providing tests, for $3000+ a pop for full BRCA gene sequencing, for 17 years before the Supreme Court invalidated key gene patents back in 2013. Since the ruling a dozen or so competitors have been … Read more
A large hereditary cancer study supports National Comprehensive Cancer Network guidance to consider risk-reducing salpingo-oophorectomy (RRSO) between ages 45 and 50 years for women with BRIP1, RAD51C, or RAD51D mutations, Lydia Usha, MD, said at the annual meeting of the … Read more
UConn Health is beginning to recruit patients for the world’s first personalized genomics-driven ovarian cancer vaccine clinical trial. The goal: to prevent an often deadly relapse of the disease in women diagnosed at advanced stages.
The pioneering injectable vaccine OncoImmunome … Read more
Hypertension, or high blood pressure, may come with a plus side, at least for a subset of women with ovarian cancer. New research from epidemiologists at Roswell Park Cancer Institute, published in the journal Cancer Causes & Control, provides evidence … Read more
