Real-World Experience Differs from Trial Results for Niraparib in Recurrent Ovarian Cancer

October 25, 2018 1:11 am

By 

Real-world experience of adverse events with the oral PARP inhibitor niraparib in patients with platinum-sensitive recurrent ovarian cancer at a 200 mg daily dose differed from those most commonly seen in the phase 3 clinical trial at … Read more

New Blood Test Could Spare Cancer Patients From Unnecessary Chemotherapy

October 17, 2018 10:02 pm

Cancer patients could be spared unnecessary chemotherapy – and its side effects – by a new blood test that is in clinical trials at more than 40 hospitals in Australia and New Zealand.

The trials, led by Melbourne researchers, are … Read more

Ovarian Cancer Thwarts Immune Cells by Revving up Stress

October 12, 2018 11:30 pm

Ovarian tumors disable the immune system’s killer T cells—which protect the body by destroying infected or malignant cells—enabling the disease to flourish unchecked, according to a new study by Weill Cornell Medicine scientists. The findings show that adverse conditions within … Read more

Crosstalk Between Fallopian Tube, Ovary May Drive the Spread of Ovarian Cancer

October 9, 2018 5:31 pm

New research from the University of Illinois at Chicago shows that cancer cells in the fallopian tube affect normal chemical signaling between reproductive tissues and stimulate the release of norepinephrine, a small molecule hormone, from the ovary.

Reported in ACS Read more

Low-Dose Aspirin May Lower Ovarian Cancer Risk

October 4, 2018 1:15 am

Women who reported recent, regular use of low-dose aspirin (100 milligrams or less) had a 23% lower risk of developing ovarian cancer when compared with women who did not regularly take aspirin, according to new research led by Harvard T.H. … Read more

BRCA1 Methylation Level May Predict Which Ovarian Cancer Patients Respond to PARP Inhibitors

September 28, 2018 8:37 pm

The extent to which the BRCA1 promoter is methylated could signal an ovarian tumor’s susceptibility to PARP inhibitor treatment, a new study has found.

PARP inhibitor treatment has been effective in treating some patients with high-grade serous ovarian carcinoma with … Read more

Novel Biomarker Found in Ovarian Cancer Patients Can Predict Response to Therapy

September 27, 2018 6:58 pm

Despite months of aggressive treatment involving surgery and chemotherapy, about 85 percent of women with high-grade wide-spread ovarian cancer will have a recurrence of their disease. This leads to further treatment, but never to a cure. About 15 percent of

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Contraceptive Pill Linked with Reduced Risk of Ovarian Cancer

September 27, 2018 5:31 pm

By 

Researchers not sure apparent protective effect extends to progestin only products such as mini pill and implants.

Women who use modern forms of the combined pill are at a lower risk of developing ovarian cancer than women … Read more

Blocking ovarian cancer’s energy supply helps curb spread

September 18, 2018 6:45 pm
It is often the case that an ovarian cancer diagnosis reveals that the tumor has already spread to nearby tissue. Now, scientists have discovered a potential way to cut off the energy supply fueling this invasive
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What’s the Evidence That Hemp Could Be Useful in Treating Cancer?

September 14, 2018 4:51 pm

By Elaine K. Howley, Contributor

It’s long been said that the Founding Fathers likely grew and possibly enjoyed using marijuana, or Cannabis sativa. But this notion, which was popularized as the fight to legalize marijuana in the early 2000s

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New Developments in Ovarian Cancer Treatment Are Showing Promise

September 14, 2018 4:29 pm

Cancer is never an easy foe, but some types are more stubborn than others. Ovarian cancer is one of the hardest to treat.

But there are signs of progress. Several recent studies have used new combination treatment strategies, including a … Read more

Study Cracks Open the Secrets of the Cancer-Causing BRCA1 Gene

September 12, 2018 12:21 am

By Sharon Begley

Lawsuits didn’t do it, public shaming didn’t do it, patients and doctors banding together to “free the data” couldn’t do it: For 22 years Myriad Genetics, one of the oldest genetic testing companies, has refused to make … Read more

Scientists Identify Mutational Signatures in Ovarian Cancer

August 22, 2018 4:52 pm

Researchers at Cancer Research UK, Imperial College London and the University of Cambridge have identified distinct patterns of genetic mutation among patients with ovarian cancer that could help them understand the disease and personalise treatment … Read more

Study: Cancer-related genetic testing is rare for women on Medicare

August 20, 2018 6:28 pm

By Health Day News

Testing for gene mutations linked to breast and ovarian cancer is rare among some Medicare patients who have the cancers and qualify for such tests, a new study finds.

Researchers analyzed data from 12 southeastern states … Read more

Memorial Sloan Kettering Researchers Build a New Model of Genetically Engineered Immune Cells That May Combat Solid Tumors in the Future

August 15, 2018 10:37 pm

Bottom Line: Scientists at Memorial Sloan Kettering Cancer Center (MSK) announced that they have built a new model of genetically engineered immune cells in mice that may allow them to fight solid tumors. The new cells combine two of the … Read more

Treating Ovarian Cancers by Targeting Mutations

July 31, 2018 11:22 pm

New research has shown that ovarian cancer patients with a tumor mutation in the BRAF gene respond exceptionally well to treatment with targeted drugs, known as BRAF inhibitors.

BRAF inhibitors block the activity of mutated BRAF gene. They are currently … Read more

Low-Dose Aspirin May Help Against Ovarian Cancer

July 27, 2018 1:12 am
By Steven Reinberg
One low-dose aspirin a day could help women avoid ovarian cancer or boost their survival should it develop, two new studies suggest.

In fact, daily low-dose aspirin — the type many older women already take to help

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Cramps or Cancer: Elevated Menstrual Pain May be Associated with Ovarian Cancer Risk

July 24, 2018 7:10 pm

BY Brielle Urciuoli

Menstrual pain is something that, unfortunately, many women will encounter at some point during their lives. However, according to a recent study published in the International Journal of Cancer, individuals may want to talk to their health … Read more

Triggering an Immune Response in Ovarian Cancer

July 17, 2018 2:04 am
by Mark L. Fuerst

A novel personalized vaccine made from an ovarian cancer patient’s tumor tissue and immune cells was found in early research to stimulate potent therapeutic immune responses, extending overall survival for patients with recurrent disease.

The vaccine,

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Study does not find causal association between assisted reproduction and ovarian cancer risk

July 12, 2018 7:04 pm

Following concerns over many years that hormonal stimulation of the ovaries necessary for IVF may increase the risk of ovarian cancer, a nationwide cohort study from Denmark has now concluded that any perceived increase in risk is actually a statistical … Read more