Information and Support

May 2, 2018 6:58 pm
There are many places you can go online to learn more about cancer and obtain financial and psycho-social support. Here are a few examples: 21st Century C.A.R.E. (888-850-1622) – Provides financial assistance, education and support. American Cancer Society (800-227-2345) – … Read more

Genomics and Individualized Therapy

May 2, 2018 6:23 pm
Molecular profiling can help inform treatment decisions for ovarian cancer patients.  Tumor profiles are discovered by testing the tumor for biomarkers, such as PD-L1, homologous recombination deficiency (HRD), tumor mutation burden (TMB), and microsatellite instability (MSI) and using next generation … Read more

Finding cancer earlier: New tests show promise with broader screening available

August 19, 2021 9:33 pm
By Meg Tully Rosemary Jemo volunteered for a blood test trial based on pioneering research from Johns Hopkins University because she thought it would be great if it could save lives. The 71-year-old Pennsylvania hairdresser now believes that decision saved … Read more

Old Antibiotic Targets BRCA-Mutated, PARP Inhibitor-Resistant Tumors

June 18, 2021 12:21 pm
Studies in laboratory cell lines and in mouse tumor models show an antibiotic developed in the 1950s called novabiocin effectively targets and kills cancer cells with abnormal BRCA1 or BRCA2 genes, which normally help to repair damaged DNA.… Read more

Universal Genetic Testing Is Far From a Reality in Patients With Ovarian Cancer

June 8, 2021 11:28 am
by Victoria Forster, PhD Rates of genetic testing in ovarian cancer “remain well below the goal of universal testing,” according to authors of a systematic review and meta-analysis published in Gynecologic Oncology.1… Read more

Electronic Olfaction System Under Study as Screening Tool for Pancreatic and Ovarian Cancers

June 5, 2021 9:00 am
An odor-based test that detects vapors emanating from blood samples was able to distinguish between benign and pancreatic and ovarian cancer cells with up to 95% accuracy, according to a new study presented by Johnson et al during the 2021 … Read more

‘Devastated and Sad’ After 36 Years of Research — Early Detection of Ovarian Cancer Doesn’t Save Lives

May 19, 2021 1:00 pm
By Professor Ian Jacobs I was motivated to improve the outcome for women with ovarian cancer by my experience as a junior doctor in London in 1985. But 36 years on, the results aren’t what we’d hoped. My colleages’ and … Read more

Disappointment: Screening for Ovarian Cancer Does Not Cut Deaths

May 13, 2021 12:00 pm
By Pam Harrison Results from a huge British trial that involved more than 200,000 women who were followed for a median of 16 years have turned out negative. Investigators found that annual screening for ovarian cancer with either multimodal screening … Read more

ARIEL2 Analysis Sheds Light on Biomarkers of Response to Rucaparib in Ovarian Cancer

May 4, 2021 2:00 pm
RAD51C and RAD51D mutations and high-level BRCA1 promotor methylation are predictive of response to rucaparib in patients with recurrent ovarian cancer, while genomic scars linked with homologous recombination deficiency is predictive of response only in those with platinum-sensitive disease. By … Read more

Two Pathways, One Destination: Promising Drug Combination to Treat Ovarian Cancer

March 15, 2021 3:00 pm
By R. Colon-Thillet Treatment for ovarian cancer across subtypes typically consists of platinum-based chemotherapies. However, this standard therapy is less effective against ovarian clear cell carcinoma (OCCC), a rare subtype of ovarian cancer with distinct pathology and genetic drivers. Advanced … Read more

Pap Test/Cervical Swab Samples Can Reveal Ovarian Cancer Biomarkers

February 22, 2021 10:00 am
By Sharon Worcester Residual fixatives from liquid-based Pap tests and cervical swabs contain tumor-specific biomarkers for ovarian cancer, according to an analysis of proteins found in matched biospecimens from a woman with high grade serous ovarian cancer. The findings suggest … Read more

Common Genetic Test Often Wrong When Identifying Rare Disease-Causing Variants Such as BRCA1 and BRCA2, Study Says

February 16, 2021 10:00 am
By Sandee LaMotte, CNN A genetic test used to detect common traits many people share is not reliable in identifying rare disease-causing variations, such as those that can predict breast and ovarian cancer, a new study has found. The SNP … Read more

SEngine Precision Medicine IDs Potential Ovarian Cancer Treatment Combos Using Organoid Approach

November 23, 2020 8:00 pm
By Caroline Hopkins Using organoids that closely model certain features of ovarian tumors, researchers have identified and tested treatment combinations that may benefit patients, many of whom experience acquired or de novo resistance to PARP inhibitors. In a study recently … Read more

Adagrasib a Promising New Treatment for Lung, Pancreatic, Endometrial, Ovarian and Colon Cancers

October 27, 2020 6:00 pm
By Mary Moore A new drug that inhibits a cancer mutation in the KRAS gene has shown encouraging results in patients with lung cancer, colon cancer, and other solid tumors. For decades, scientists have been trying to develop new … Read more

How Does Ovarian Cancer Form? A New Study Points to MicroRNA

July 30, 2020 4:00 pm
Although ovarian cancer is the fifth-leading cause of death from cancer in women, scientists don’t have a good handle on how it forms. Now a new study suggests that a microRNA—a molecule made by cells to turn genes on … Read more

Chemotherapy, Surgery for Gynecologic Cancer Not Linked to Higher COVID-19 Mortality Risk

July 30, 2020 3:00 pm
Women who underwent chemotherapy or surgery for gynecologic cancer and also had COVID-19 infection did not appear at significantly increased risk for death due to the novel coronavirus, according to study findings published in Cancer. However, recent immunotherapy use … Read more

Universal BRCA Testing Could Prevent Countless Cancer Deaths

July 17, 2020 1:00 pm
By Diana Swift Population screening found to be cost-effective for higher income countries Screening entire populations of women for mutations in breast and ovarian cancer susceptibility genes could prevent hundreds of thousands of cases in the U.S., and millions globally, … Read more

Blood Test Detects Dozens of Cancer Types, Often Before Symptoms Emerge

July 13, 2020 5:00 pm
A novel blood test accurately detected more than 50 types of cancer with a specificity of 99.3%. By Mark Leiser A novel blood test accurately detected more than 50 types of cancer with a specificity of 99.3%, according to results … Read more

Certain Recurring Symptoms May Be Linked to Ovarian Cancer

July 13, 2020 2:00 pm
A recent data analysis found that most women diagnosed with ovarian cancer (92%) experienced abdominal and pelvic-related symptoms and visited a physician with this complaint anywhere from six to 70 months prior to diagnosis. By Ryan McDonald Data from a … Read more

Pap Tests May Hold Biomarkers Ahead of Ovarian Cancer Diagnosis

July 10, 2020 4:00 pm
High-grade serous epithelial ovarian cancer may be detected earlier in the course of the disease by testing for TP53 clonal variants in DNA from Pap tests. By Leah Lawrence High-grade serous epithelial ovarian cancer may be detected earlier in the … Read more