Pemetrexed Resistance Marker

Pemetrexed Resistance Marker
Marker	Name	Biological Role	Evidence	References
TS	Thymidylate synthase	Synthesizes dTMP required for DNA synthesis	High TS expression correlated with poor efficacy and outcome in NSCLC and mesothelioma patients treated with pemetrexed-based therapy	Pemetrexed Resistance: TS References

Marker

Name

Biological Role

Evidence

References

Thymidylate synthase

Synthesizes dTMP required for DNA synthesis

High TS expression correlated with poor efficacy and outcome in NSCLC and mesothelioma patients treated with pemetrexed-based therapy