Capecitabine Sensitivity Markers

Capecitabine Sensitivity Markers
Marker Name Biological Role Evidence References
TP Thymidine phosphorylase Generates 5FU from pro-drug High TP protein expression or high ratio of TP to DPD associated with good response in colorectal, esophageal, lung, and breast cancer patients following capecitabine therapy Capecitabine Sensitivity: TP and TP/DPD ratio References