About Clearity

Our Mission

Clinical Advancements & Essential Resources for Women Fighting Ovarian Cancer

Clearity Foundation strives to improve the survival and quality of life of women with ovarian cancer. We give hope to women with ovarian cancer and their families.

Founded in 2008 by scientist and survivor Laura Shawver, Ph.D., Clearity Foundation seeks to revolutionize ovarian cancer treatment. Every year, more than 22,000 women are diagnosed with ovarian cancer. Unfortunately, survival improvements are decades behind other cancers. Clearity is working to change that.

Clearity believes that all women deserve the best possible therapies for their unique disease. To achieve this, we:

  • Share the latest information on treatment options.
  • Help women access the most useful and comprehensive tests to better understand the molecular profile of their cancer.
  • Guide women to clinical trials where appropriate.
  • Provide an online community with information and social support.

The Details

Clearity takes a comprehensive, hands-on approach to help women identify the treatments that may work best against their unique disease. Assessing their medical history, as well as tumor molecular profiles and other diagnostics, Clearity professionals help women and their physicians chart the most advantageous course of treatment.

When a treatment decision needs to be made, Clearity provides information about the standard options for each patient’s clinical situation, as well as access to genomic information about their cancer to help inform their decision-making.

Clearity offers Tumor Blueprints, which identify the molecular characteristics in a tumor that may be driving its growth and survival. The Blueprint is generated by measuring specific protein biomarkers and genetic variations in a patient’s cancer and linking those findings to potential treatments. The online, interactive Tumor Blueprint Report provides results from each patient’s molecular profile, including drugs that may be most effective.

This profile can help prioritize treatment options already being considered by the clinical team and may also suggest options they have not yet considered, including off-label medicines or drugs being tested in clinical trials. Clearity experts review this information with patients, answer their questions about the results and help them find clinical trials when appropriate.

Clearity also offers assistance for women who do not want to get their tumor profiled or have already obtained a tumor profile and want help understanding it. As with those receiving Tumor Blueprints, Clearity can discuss standard of care options and identify appropriate trials.

Clearity does not provide medical advice about which treatments they should receive. Instead, our staff explain Tumor Blueprint results and provide potential questions, and other information, that patients can discuss with their physicians.

All of Clearity’s services are provided free of charge. We believe all patients should have access to the most advanced care, personalized for them, regardless of their ability to pay.

Advancing Care

Since 2008, Clearity has profiled tumors for hundreds of women. The Clearity database records the results from each woman’s Tumor Blueprint, along with information about the therapies they received and how well they worked.

Matching molecular profiles with outcomes provides additional evidence to help guide treatment decisions. Clearity has created a separate data repository that stores privacy-protected clinical and tumor profiling data. As this database grows, it supports research studies and helps Clearity provide more up-to-date information about the therapies being considered by the women and physicians who come to Clearity for support and scientific guidance.

Someone Who Listens

Clearity exists to help women find credible information about their ovarian cancer and the treatments that can help them survive. We are scientists, but we also know that cancer’s impact goes way beyond a clinical diagnosis. Our goal is to understand each patient’s unique priorities and needs. That means long, purposeful discussions informed by both science and compassion.